Angiotensin I-converting enzyme (ACE) inhibitory activity and structural properties of oven- and freeze-dried protein hydrolysate from fresh water fish (Cirrhinus mrigala)

Elavarasan, K.; Shamasundar, B.A.; Badii, Farah; Howell, Nazlin K.

doi:10.1016/j.foodchem.2016.03.047

Cited by 80 publications

(47 citation statements)

References 34 publications

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“…[38] The presence of β sheet in secondary structure is indicated at wave number 1638 cm −1. [39] In the present study, it is likely that the presence of β secondary structure cannot be ruled out as there is a peak at wave number of 1642 cm −1 as amide I band. The amide I band arises mainly due to C = O stretching vibrations (80%) and to lesser extent because of C-N stretching vibration (20%) of peptide linkages.…”

Section: Fourier Transform Infrared Spectroscopy (Ft-ir)mentioning

confidence: 67%

Structural properties of gelatin extracted from croaker fish (Johnius sp) skin waste

Kumar

Chandra

Elavarasan

et al. 2017

International Journal of Food Properties

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In the present study, the gelatin from fresh croaker fish (Johnius sp) skin was obtained by rapid extraction and its properties were assessed. The gelling and melting temperature of croaker skin gelatin was 17.4 and 23.8°C as revealed by dynamic visco-elastic analysis using Controlled Stress Rheometer. Croaker skin gelatin (CSG) had the bloom value of 193.4 g. Scanning electron microscopic analysis of freeze dried gelatin showed the presence of voids surrounded by a loose network imitating a sponge or coral like structure. Texture profile parameters such as hardness, springiness, cohesiveness, gumminess, and chewiness of croaker fish skin gelatin gel were relatively lower than the porcine gelatin gel. The amino acid composition of gelatin revealed a higher proportion of glycine, alanine, and hydroxyl proline (30.25, 23.4, and 11.82 g/100 g protein, respectively) content. The electrophoretic analysis showed the presence of two peptide chains with the approximate molecular weight of 200 and 116 kDa corresponds to β and α peptide chain of collagen. The Fourier Transform Infrared (FT-IR) spectra of gelatin showed peaks correspond to the structures like α helix, β sheet, and random coil in the gelatin preparations.ARTICLE HISTORY

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Section: Fourier Transform Infrared Spectroscopy (Ft-ir)mentioning

confidence: 67%

Structural properties of gelatin extracted from croaker fish (Johnius sp) skin waste

Kumar

Chandra

Elavarasan

et al. 2017

International Journal of Food Properties

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“…Although crude proteases extracts (e.g., from fish) have been successfully used as catalysts in enzymatic hydrolysis Lassoued et al, 2015b), commercially purified enzymes are preferably employed since they allow a better control over the hydrolysis process (e.g., shorter reaction time for a desired DH, more consistent peptides size and composition) (Samaranayaka and Li-Chan, 2011). Consequently, industrial proteases derived from different sources such as microorganisms (e.g., Alcalase, Neutrase, Protease P "Amano" 6, Flavourzyme, Protamex) (Halldorsdottir et al, 2013;Venuste et al, 2013), animals (e.g., PTN, pepsin, trypsin, a-chymotrypsin, pancreatin) (Wu et al, 2015a, b;Garc ıa-Moreno et al, 2017) and plants (e.g., papain, bromelain) (Salampessy et al, 2015;Elavarasan et al, 2016) have been widely employed for the production of protein hydrolysates exhibiting bioactive and/or functional properties. These marketable proteases may mainly contain endopeptidases (e.g., trypsin, subtilisin, papain), or a combination of endopeptidases and exopeptidases (e.g., carboxypeptidases, aminopeptidases).…”

Section: Enzymatic Protein Hydrolysismentioning

confidence: 99%

Peptides: Production, bioactivity, functionality, and applications

Hajfathalian

Ghelichi

Moreno

et al. 2017

Critical Reviews in Food Science and Nutrition

133

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Production of peptides with various effects from proteins of different sources continues to receive academic attention. Researchers of different disciplines are putting increasing efforts to produce bioactive and functional peptides from different sources such as plants, animals, and food industry by-products. The aim of this review is to introduce production methods of hydrolysates and peptides and provide a comprehensive overview of their bioactivity in terms of their effects on immune, cardiovascular, nervous, and gastrointestinal systems. Moreover, functional and antioxidant properties of hydrolysates and isolated peptides are reviewed. Finally, industrial and commercial applications of bioactive peptides including their use in nutrition and production of pharmaceuticals and nutraceuticals are discussed.

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“…Therefore, in the development of drugs to control high blood pressure, ACE inhibitors and angiotensin receptor blockers are now used clinically for the treatment of various cardiovascular diseases [58]. However, the synthetic drugs such as captopril, lisinopril, and enalapril [59] are believed to have certain side effects such as a cough, skin rash, loss of taste, or angioneurotic oedema [60, 61]. Due to these adverse side effects, there is a trend towards encouraging the development of natural ACE inhibitors.…”

Section: Marine Peptides With Different Bioactivitiesmentioning

confidence: 99%

Characterization, Preparation, and Purification of Marine Bioactive Peptides

Wang

Xing

et al. 2017

BioMed Research International

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Marine bioactive peptides, as a source of unique bioactive compounds, are the focus of current research. They exert various biological roles, some of the most crucial of which are antioxidant activity, antimicrobial activity, anticancer activity, antihypertensive activity, anti-inflammatory activity, and so forth, and specific characteristics of the bioactivities are described. This review also describes various manufacturing techniques for marine bioactive peptides using organic synthesis, microwave assisted extraction, chemical hydrolysis, and enzymes hydrolysis. Finally, purification of marine bioactive peptides is described, including gel or size exclusion chromatography, ion-exchange column chromatography, and reversed-phase high-performance liquid chromatography, which are aimed at finding a fast, simple, and effective method to obtain the target peptides.

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Angiotensin I-converting enzyme (ACE) inhibitory activity and structural properties of oven- and freeze-dried protein hydrolysate from fresh water fish (Cirrhinus mrigala)

Cited by 80 publications

References 34 publications

Structural properties of gelatin extracted from croaker fish (Johnius sp) skin waste

Structural properties of gelatin extracted from croaker fish (Johnius sp) skin waste

Peptides: Production, bioactivity, functionality, and applications

Characterization, Preparation, and Purification of Marine Bioactive Peptides

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