Angiolymphoid hyperplasia with eosinophilia

Abstract

Angiolymphoid hyperplasia with eosinophilia is manifested by benign vascular tumors that usually occur about the head in young adults. Clinical and histologic variation of this process has resulted in nosologic confusion, and the cases in the English literature were reviewed to characterize it within racial groups. Oriental patients tend to be younger at onset, usually male, and have marked blood eosinophilia; large, but relatively asymptomatic, tumors develop in these patients. White patients tend to be older at onset and have small, friable tumors. Large tumors that are painful or pruritic tend to develop in blacks and Middle Eastern patients.

A Woman with a Lower Lip Nodule: What Is Your Diagnosis?

“…ALHE was originally thought to affect the head or neck of young women [8]. However, several reviews show a wide age range of affected persons peaking at 20–50 years without a sexual predominance [9, 10].…”

“…However, several reviews show a wide age range of affected persons peaking at 20–50 years without a sexual predominance [9, 10]. ALHE occurs commonly on the head and neck with a predilection for the forehead, scalp, and skin around ears [8–10]. Though rare, this condition has been reported to occur on the trunk, breast, vulva [11], and the penis [12].…”

Angiolymphoid Hyperplasia with Eosinophilia That Was Possibly Induced by Vaccination in a Child

“…Clinically, ALHE presents as single or multiple pink to reddish-brown papules or subcutaneous nodules that are usually located on the head and neck, and especially in the preauricular region, and ALHE generally occurs in young adults 9 . It has been described less frequently at other sites 10,11 and in children 12,13 .…”

Angiolymphoid hyperplasia with eosinophilia

“…Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare condition of uncertain aetiology. There are wide racial differences in presentation, with oriental patients being predominantly male (85 percent) and young (second decade) in contrast to western cases which tend to occur in females (70 per cent) and older patients (third or fourth decades) (Henry and Burnett, 1978). It causes papular or nodular angiomatous lesions in the dermis, subcutaneous tissues and adjacent lymph nodes, which average 1 cm in diameter (Kung et al, 1984).…”