Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia

Efficacy of tamoxifen andl-carnitine on sperm ultrastructure and seminal oxidative stress in patients with idiopathic oligoasthenoteratozoospermia

“…In the present study, all sperm parameters except tail anomalies were improved after tamoxifen treatment. This agrees with a number of uncontrolled trials suggesting improvement in all semen parameters and pregnancy rates with the use of anti‐estrogens for idiopathic infertility (Allag & Alexander, ; Bartsch & Scheiber, ; Adamopoulos, ; Vandekerckhove et al ., ). Kotoulas et al .…”

Efficacy of tamoxifen andl-carnitine on sperm ultrastructure and seminal oxidative stress in patients with idiopathic oligoasthenoteratozoospermia

“…In the present study, all sperm parameters except tail anomalies were improved after tamoxifen treatment. This agrees with a number of uncontrolled trials suggesting improvement in all semen parameters and pregnancy rates with the use of anti‐estrogens for idiopathic infertility (Allag & Alexander, ; Bartsch & Scheiber, ; Adamopoulos, ; Vandekerckhove et al ., ). Kotoulas et al .…”

Microscopic testicular sperm extraction or post-operative sperm reversal in functional Leydig cell tumor: case report

“…After left orchidectomy of the tumor, androgen secretion decreased, and there could have been a surge of FSH and LH, with spermatogenesis recommencing. However, the androgen rebound effect cannot be maintained for more than four months because of the spermatogenic cycle and the transient secretion surge of sex hormones (14,15). Sperm cryopreservation is strongly recommended at three months postoperatively and no more than four months.…”

The advantages of standardized evaluation of male infertility

“…However, the randomized controlled trials were inconclusive with respect to pregnancy rates. Gonadotrophins and antioestrogens as empirical treatment for normogonadotrophic infertile men were not effective in relatively small study groups, although the beneficial effect was bordering on significance (Vandekerckhove et al ., 1998). The rationale for treatment of male infertility with antioestrogens is based on counteracting the normal negative feedback on the hypothalamus‐pituitary‐testis axis by oestrogens.…”

Efficacy of tamoxifen andl-carnitine on sperm ultrastructure and seminal oxidative stress in patients with idiopathic oligoasthenoteratozoospermia

“…In the present study, all sperm parameters except tail anomalies were improved after tamoxifen treatment. This agrees with a number of uncontrolled trials suggesting improvement in all semen parameters and pregnancy rates with the use of anti‐estrogens for idiopathic infertility (Allag & Alexander, ; Bartsch & Scheiber, ; Adamopoulos, ; Vandekerckhove et al ., ). Kotoulas et al .…”

Microscopic testicular sperm extraction or post-operative sperm reversal in functional Leydig cell tumor: case report

“…After left orchidectomy of the tumor, androgen secretion decreased, and there could have been a surge of FSH and LH, with spermatogenesis recommencing. However, the androgen rebound effect cannot be maintained for more than four months because of the spermatogenic cycle and the transient secretion surge of sex hormones (14,15). Sperm cryopreservation is strongly recommended at three months postoperatively and no more than four months.…”

The advantages of standardized evaluation of male infertility

“…However, the randomized controlled trials were inconclusive with respect to pregnancy rates. Gonadotrophins and antioestrogens as empirical treatment for normogonadotrophic infertile men were not effective in relatively small study groups, although the beneficial effect was bordering on significance (Vandekerckhove et al ., 1998). The rationale for treatment of male infertility with antioestrogens is based on counteracting the normal negative feedback on the hypothalamus‐pituitary‐testis axis by oestrogens.…”

Efficacy of tamoxifen andl-carnitine on sperm ultrastructure and seminal oxidative stress in patients with idiopathic oligoasthenoteratozoospermia

“…In the present study, all sperm parameters except tail anomalies were improved after tamoxifen treatment. This agrees with a number of uncontrolled trials suggesting improvement in all semen parameters and pregnancy rates with the use of anti‐estrogens for idiopathic infertility (Allag & Alexander, ; Bartsch & Scheiber, ; Adamopoulos, ; Vandekerckhove et al ., ). Kotoulas et al .…”

Microscopic testicular sperm extraction or post-operative sperm reversal in functional Leydig cell tumor: case report

“…After left orchidectomy of the tumor, androgen secretion decreased, and there could have been a surge of FSH and LH, with spermatogenesis recommencing. However, the androgen rebound effect cannot be maintained for more than four months because of the spermatogenic cycle and the transient secretion surge of sex hormones (14,15). Sperm cryopreservation is strongly recommended at three months postoperatively and no more than four months.…”

The advantages of standardized evaluation of male infertility

“…However, the randomized controlled trials were inconclusive with respect to pregnancy rates. Gonadotrophins and antioestrogens as empirical treatment for normogonadotrophic infertile men were not effective in relatively small study groups, although the beneficial effect was bordering on significance (Vandekerckhove et al ., 1998). The rationale for treatment of male infertility with antioestrogens is based on counteracting the normal negative feedback on the hypothalamus‐pituitary‐testis axis by oestrogens.…”