Ancient papillomavirus-host co-speciation in Felidae

Abstract

Virus-host co-speciation <p>The evolutionary rate of feline papillomaviruses is inferred from the phylogenetic analysis of their hosts, providing evidence for longterm virus-host co-speciation</p> Abstract Background: Estimating evolutionary rates for slowly evolving viruses such as papillomaviruses (PVs) is not possible using fossil calibrations directly or sequences sampled over a time-scale of decades. An ability to correlate their divergence with a host species, however, can provide a means to estimate evolutionary rates for these viruses accurately. To determine whether such an approach is feasible, we sequenced complete feline PV genomes, previously available only for the domestic cat (Felis domesticus, FdPV1), from four additional, globally distributed feline species: Lynx rufus PV type 1, Puma concolor PV type 1, Panthera leo persica PV type 1, and Uncia uncia PV type 1.

Oral Papillomas Associated With Felis catus Papillomavirus Type 1 in 2 Domestic Cats

“…6 As observed in the 2 domestic cats, oral papillomas in the exotic felids typically appear as multiple small raised plaques on the ventral surface of the tongue. The oral papillomas of exotic felids are also histologically similar to those of domestic cats and, in contrast to most nonfeline species, typically contain prominent PV cytopathic changes.…”

Isolation and genomic characterization of the first Norway rat (Rattus norvegicus) papillomavirus and its phylogenetic position within Pipapillomavirus, primarily infecting rodents

“…Approximately 150 PV genomes, isolated from humans and different animal species, have been cloned and completely sequenced so far (Van Ranst et al, 1992;Terai et al, 2002;Forslund et al, 2003;Rector et al, 2007). However, the number of known non-human host species is still low (approx.…”

“…In the past years, phylogenetic analytical methods have been applied more rigorously for the reconstruction of PV evolution (García-Vallvé et al, 2005;Narechania et al, 2005;Rector et al, 2007). Four PV supertaxa have been identified, namely a+o-, b+c+p+j-, d+e-and k+l+m+n+s-PVs (Gottschling et al, 2007b), and most known PV types can be classified into one of them.…”

“…Most reliable evolutionary rates for PVs, ranging between 1.44610 28 and 2.69610 28 s/b/y, have been inferred from congruent phylogenies between members of the Carnivora and the genus Lambdapapillomavirus (l-PV; Rector et al, 2007). However, timing other viral groups may prove difficult, even if, for example, rodent phylogenetic trees (Huchon et al, 2002;Montgelard et al, 2008) and PV trees were indeed congruent: the age of the Rodentia, and therefore a possible calibration point, is controversially debated at present (Adkins et al, 2003).…”

Prevalence, Emergence, and Factors Associated with a Viral Papillomatosis and Carcinomatosis Syndrome in Wild, Reintroduced, and Captive Western Barred Bandicoots (Perameles bougainville)

“…Due to its similarity to other small DNA viruses such as papillomaviruses and polyomaviruses, BPCV1 is likely an ancient and speciesspecific virus that has co-evolved with its WBB host (Van Ranst et al 1995;Crandall et al 2006;Perez-Losada et al 2006;Rector et al 2007). A second, highly similar but distinctly different virus, BPCV2, was recently detected in papillomatous skin lesions from a mainland southern brown bandicoot (Isoodon obesulus) in Western Australia .…”