Analysis of Uranium Mobility and Concentration Process in Objects of Environment and Patients’ Kidney Stones in Kharkiv Region

Dikiy, N.P.; Lisovoy, V.N.; Bereznyak, E.P.; Kolupayev, S. M.; Lyashko, Yu.V.; Medvedeva, E.P.; Medvedev, D. V.; Hodyreva, Y.S.

doi:10.46813/2021-133-119

Cited by 3 publications

(5 citation statements)

References 9 publications

(7 reference statements)

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“…It was documented that, the existence of uranium isotopes in groundwater is related to the hydrothermal, geochemical, and mineralogical conditions of the aquifers 35,36 . Uranium mobility to urinary stones was confirmed in the literature using a gamma spectrometer, and it might have a role in the formation of a specific type of urinary stones 37,38 . The divalent uranium compounds have the ability to deposit on the surface of hydroxyapatite crystal by ion exchange of Ca +2 ions, and it is strongly bound with two phosphate groups 38 .…”

Section: Main Results Obtainedmentioning

confidence: 97%

“…Trivalent and pentavalent uranium compounds could be found soluble in water and air whereas other oxidation states exist in solid states such as soil and rocks. The elevation of uranium concentration in drinking water and groundwater may cause uranium accumulation in the kidney and consequently in urinary stones, which could have a harmful renal effect and produce chemical changes in renal tubules 37,39,40 …”

Section: Main Results Obtainedmentioning

confidence: 99%

“…35,36 Uranium mobility to urinary stones was confirmed in the literature using a gamma spectrometer, and it might have a role in the formation of a specific type of urinary stones. 37,38 The divalent uranium compounds have the ability to deposit on the surface of hydroxyapatite crystal by ion exchange of Ca +2 ions, and it is strongly bound with two phosphate groups. 38 In the case of the existence of uranium in urinary stone samples, as the concentration of uranium increases as found in #7U (314 ± 12 μg/g), the probability of chemical toxicity to human health regardless of the radioactivity of natural or depleted uranium increases.…”

Section: Uranium In the Urinary Stonesmentioning

confidence: 99%

“…The elevation of uranium concentration in drinking water and groundwater may cause uranium accumulation in the kidney and consequently in urinary stones, which could have a harmful renal effect and produce chemical changes in renal tubules. 37,39,40…”

Section: Uranium In the Urinary Stonesmentioning

confidence: 99%

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Elemental and statistical analysis of small individual urinary stones using TXRF spectrometry

et al. 2023

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Due to the small quantity of most of the extracted human urinary stone samples, there is an urgent need for an analytical technique that is able to perform a multi‐elemental quantitative analysis for a small fraction of these samples. In the present work, a few milligrams of different types of urinary stones were microwave digested in ultra‐pure nitric acid, and the elemental determination was achieved by total reflection X‐ray fluorescence (TXRF). The elements P, S, Ca, Fe, Cu, Zn, Se, and Sr were detected in most of the different stones. However, the trace elements: K, Ti, V, Cr, Mn, Ni, As, Pb, and U were also found in a certain number of samples. Furthermore, inductively coupled plasma optical emission spectrometry (ICP‐OES) was used and the elements Mg, Ti, Mn, Cu, Zn, and Cd were determined. A good agreement between the results of TXRF and ICP‐OES was obtained with respect to the elements Ti, Mn, Cu, and Zn. Cadmium and magnesium were only determined by ICP‐OES. More attention was given to the existence and the spectral interference of As‐Kα and Pb‐Lα as well as As‐Kβ and Br‐Kα in a limited number of urinary stones. Based on the analysis of variance and Pearson's correlation analysis, an additional statistical analysis study was performed in terms of quantified elements and the types of urinary stones. Calcium has a remarkable positive correction with Ni, Zn, and P, whereas a negative correlation was found with K, S, and Cu. Based on the hierarchical cluster analysis, the square Euclidean showed four main groups of urinary stones starting with high to trace amounts of calcium oxalate. Furthermore, the squared Euclidean showed further subgroups of the urinary stones. The role of certain elements in terms of forming or inhabiting the urinary stone formation was discussed. Uranium was determined in a limited number of urinary stones using TXRF and ICP‐OES. The origin of the uranium may be the drinking and groundwater. Uranium could be accumulated in the urinary stones from these sources. In addition, the divalent uranium compounds can deposit on the surface of hydroxyapatite crystal, which is one of the main compounds in the urinary stones.

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Section: Main Results Obtainedmentioning

confidence: 97%

Section: Main Results Obtainedmentioning

confidence: 99%

Section: Uranium In the Urinary Stonesmentioning

confidence: 99%

Section: Uranium In the Urinary Stonesmentioning

confidence: 99%

See 2 more Smart Citations

Elemental and statistical analysis of small individual urinary stones using TXRF spectrometry

et al. 2023

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“…As a rule, environmental factors are dierent in each biogeocenosis and therefore they are able to greatly enhance or weaken the biological eect of radiation factors. Even low levels of radiation (α, β and γ-emitters), which are classied as low doses, can accumulate in environmental objects (soil, water, plants) [1][2][3] and subsequently have a negative impact on the human body. Therefore, the problem of low doses is actual and has not been suciently studied so far.…”

Section: Introductionmentioning

confidence: 99%

Synergism and Antagonism of Influence Low Dose Radiation and Environment on Health of Population in Ukraine

Dikiy¹,

Medvedeva²

2019

Problems of Atomic Science and Technology

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The genesis of carcinogenic diseases is characterized by a multifactor dependence. The effect of low dose radiation in combination with environmental factors has a significant number of features. It was studied the influence of certain features of the environment and the mental state of the person (affect) on the development of the incidence of carcinogenic diseases of the population in Ukraine. Given the various adverse environmental conditions, the effect of radiation in low doses can be enhanced or weakened. Synergism and antagonism of the effect of low dose radiation and environment on the health of the population are discussed.

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Translyumbal Elektroi̇mpuls Sti̇mulyasi̇yasinin Ureteroli̇ti̇azli Pasi̇yentlərdə Si̇di̇k Axarlarinin Peri̇stalti̇k Akti̇vli̇yi̇nə Təsi̇ri̇

Колупаев,

Лесовой,

Андоньева

et al. 2022

Azerbaijan Medical Journal

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В статье представлены результаты исследования, проведенного с целью изучения влияния транслюмбальной электроимпульсной стимуляции пейсмейкерной зоны почечной лоханки и пиелоуретерального сегмента на перистальтическую активность мочеточника у пациентов с уретеролитиазом. В исследование были включены 54 пациента, в возрасте 22-67 лет, мужчин – 31, женщин – 23, с камнями мочеточников. Размеры камней варьировали в диапазоне 4-7 мм, единичные камни имели место у 40 (74,1%) больных, множественные – у 14 (25,9%) обследуемых. После оценки исходной частоты мочеточниковых выбросов у больных с уретеролитиазом проводили транслюмбальную электроимпульсную стимуляцию на стороне обструкции с помощью электромиографа по оригинальной методике. В ходе исследования установлено изменение перистальтической активности мочеточника. Воздействие хорошо переносилось пациентами. Изменений показателей гемодинамики выявлено не было. Таким образом, транслюмбальная электроимпульсная стимуляция пейсмейкерной зоны почечной лоханки и пиелоуретерального сегмента является эффективным методом стимуляции перистальтической активности мочеточника и может применяться в комплексе лечебных мероприятий экспульсивной терапии у пациентов с уретеролитиазом. Məqalədə böyrək ləyənciyinin və pielouretral seqmentin peysmeyker zonalarının translyumbal elektroimpuls stimulyasiyasının urolitiazlı xəstələrdə sidik axarlarının peristaltik aktivliyinə təsirini öyrənmək məqsədilə aparılmış tədqiqat haqqında məlumat verilmişdir. Tədqiqata yaşı 20-dən 67-yə qədər olan 54 (31 kişi, 23 qadın) ureterolitizalı xəstə cəlb edilmişdir. Daşların ölçüləri 4-7 mm arasında olmuş, xəstələrdən 40 nəfərdə (71%) tək, 14 nəfərdə (25,9%) çoxsaylı sidik daşları olmuşdur. Urolitiazlı xəstələrdə sidik axarlarının yığılmasının ilkin tezliyi müəyyənləşdirildikdən sonra elektromioqrafiyadan istifadə edilməklə obstruksiya olan tərəfdə orijinal metod üzrə elektroimpuls stimulyasiyası aparılmışdır. Tədqiqat zamanı sidik axarlarının peristaltik aktivliyi tədqiq edilmişdir. Xəstələr bu proseduru yaxşı keçirmişlər; hemodinamik göstəriciləri dəyişikliyə uğramayıb. Beləliklə, böyrək ləyənlərinin və pielouretral seqmentin peysmeyker zonalarının translyumbal elektroimpuls stimulyasiyası onların peristaltik aktivliyinə təsir göstərən effektiv metoddur və bu metoddan ureterolitiazlı xəstələrin müalicə kompleksində istifadə edilə bilər. The article presents the results of a study conducted in order to study the effect of translumbar electrical impulse stimulation of the pacemaker zone of the renal pelvis and pyeloureteral segment on the peristaltic activity of the ureter in patients with ureterolithiasis. The study included 54 patients aged 22-67 years, 31 men and 23 women with ureteral stones. The size of the stones varied in the range of 4-7 mm, single stones occurred in 40 (74.1%) patients, multiple – in 14 (25.9%) patients. After assessing the initial frequency of ureteral emissions in patients with ureterolithiasis, translumbar electrical impulse stimulation was performed on the side of obstruction using an electromyograph according to the original method. During the study, a change in the peristaltic activity of the ureter was established. The impact was well tolerated by patients. There were no changes in hemodynamic parameters. Summarizing, translumbar electrical impulse stimulation of the pacemaker zone of the renal pelvis and pyeloureteral segment is an effective method of stimulating the peristaltic activity of the ureter and can be used in a complex of therapeutic measures of expulsive therapy in patients with ureterolithiasis.

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Analysis of Uranium Mobility and Concentration Process in Objects of Environment and Patients’ Kidney Stones in Kharkiv Region

Cited by 3 publications

References 9 publications

Elemental and statistical analysis of small individual urinary stones using TXRF spectrometry

Elemental and statistical analysis of small individual urinary stones using TXRF spectrometry

Synergism and Antagonism of Influence Low Dose Radiation and Environment on Health of Population in Ukraine

Translyumbal Elektroi̇mpuls Sti̇mulyasi̇yasinin Ureteroli̇ti̇azli Pasi̇yentlərdə Si̇di̇k Axarlarinin Peri̇stalti̇k Akti̇vli̇yi̇nə Təsi̇ri̇

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