Analysis of triazines by capillary electrochromatography/electrospray ionization‐mass spectrometry using a low‐flow sheath liquid interface

Abstract

CEC-MS has been used for the analysis of eight-triazine herbicides. It showed significantly better S/N ratio than reversed EOF CE-MS and MEKC-MS, due to the lack of a surfactant in the separation buffer. By optimizing the pH, the organic content of the running buffer, and the separation potential, optimal separation was achieved within 18 min using a running buffer of pH 7.0, containing 70% v/v ACN, and an applied voltage of 17 kV. Gradient CEC showed superior separation when compared with isocratic elution. The combination of a tapered CEC column and a low-flow interface confers several advantages including better sensitivity, low dead volume, and independent control of the conditions used for CEC separation and ESI analysis.

Trends in CE‐MS 2005–2006

“…Moreover, most of the coupling methods applied are built-up or developed in-house and experience in the fabrication and handling is needed [36]. As has been also reviewed by Klampfl [4], developments of the interface were reported [36,37], although more papers address better solutions for the capillary fabrication such as the use of novel separation materials [38][39][40][41], improvements of the packing method [42] or alternations of the separation capillary [43].…”

Evaluation of band broadening in chemiluminescence detection coupled to pressurized capillary electrochromatography with an off‐column coaxial flow interface

“…Latest developments on this field include the use of LIF [7,8], mass spectrum [9,10], electrochemical [11,12], and NMR [13,14] detectors. Chemiluminescence (CL), characterized by simple optical systems and extremely low background noise, is an alternative sensitive detection technique suited to the need of low-volume, on-line detection in pCEC.…”

Recent advances in CE and CEC of pollutants

“…The coupling of MEKC with MS is still in its very early stages. In the past 2 years, new CE/MEKC/CEC-ESI-MS methods have been developed for determining pharmaceuticals [49], pesticides and triazines [50,51], organic acids [52], biodegradation products from sulfonated dyes [53], dialkylphthalates [47], PAHs [54], amines [55], nitrosamines [56], explosives [57,58], and surfactants [59,60].…”