Abstract:Background: The Prostate Cancer Prevention Trial (PCPT) has challenged the validity of recommended prostate-specific antigen (PSA) thresholds for prostate biopsy (> 2.5 ng/ml) given the 17% prostate cancer (pCA) detection rate at PSA of 1.1-2.0. The outcome of patients treated at PSA < or = 2.5 is poorly defined, and advantages associated with such an early diagnosis are uncertain. Objective: Compare the outcome of patients with T1c pCA with pretreatment PSA < or = 2.5 and 2.6-4.0. Design, Setting, And Partici… Show more
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