Analysis of risk factors of PICC-related bloodstream infection in newborns: implications for nursing care

Abstract

Background It is necessary to analyze the characteristics and risk factors of catheter-related bloodstream infection (CRBSI) in newborns with peripherally inserted central catheter (PICC). Methods Newborns undergoing PICC catheterization in the neonatal department of our hospital from January 1, 2020 to January 31, 2021 were included. The characteristics of newborns with and without CRBSI newborns were compared and analyzed. Logistic regression analyses were performed to evaluate the risk factors of CRBSI in newborns with PICC. Results Three hundred eighty-six newborns with PICC were included, of whom 41 newborns had the CRBSI, the incidence of CRBSI in newborns with PICC was 10.62%. There were significant differences regarding the birth weight, durations of PICC stay, 5-min Apgar score, site of PICC insertion of PICC between CRBSI and no CRBSI group (all P < 0.05), and there were no significant differences regarding the gender, gestational age, cesarean section, mechanical ventilation and length of hospital stay between CRBSI and no CRBSI group (all P > 0.05). Escherichia coli (26.08%) and Staphylococcus aureus (23.92%) were the most common CRBSI pathogens in newborns with PICC. Logistic regression analysis indicated that birth weight ≤ 1500 g (OR 1.923, 95% CI 1.135–2.629), durations of PICC stay ≥ 21 days (OR 2.077, 95% CI 1.024–3.431), 5-min Apgar score ≤ 7 (OR 2.198, 95% CI 1.135–3.414) and femoral vein insertion of PICC (OR 3.044, 95% CI 1.989–4.306) were the independent risk factors of CRBSI in neonates with PICC (all P < 0.05). Conclusion For newborns with low birth weight, longer durations of PICC stay and femoral vein PICC insertion, they may have higher risks of CRBSI, and medical staff should take targeted measures to reduce the development of CRBSI.

Effects of Peripherally Inserted Central Catheter (PICC) Catheterization Nursing on Bloodstream Infection in Peripheral Central Venous Catheters in Lung Cancer: A Single-Center, Retrospective Study

“…With the widespread use of peripheral central venous cannulae in the treatment of cancer patients, it has been found that complications from PICC-induced bloodstream infections are gradually gaining the attention of physicians and patients [ 9 ]. Once a bloodstream infection is formed, it will inevitably increase the physical and mental burden of the patient and at the same time reduce the initiative and motivation of the patient, which ultimately affects the prognosis to a great extent [ 10 ]. Relevant research data show that the mortality rate of bloodstream infections due to PICC is about 11.6% [ 11 ].…”

Indications, Measurements, and Complications of Ten Essential Neonatal Procedures

“…Although the PICC provides the mainstay of long-term, International Journal of Pediatrics stable venous access, its complications remain a concern. Peripherally inserted central catheter is associated with increased risks of catheter-related bloodstream infection [72], thrombosis [73,74], extravasation and intrahepatic collections of hyperalimentation [75], massive consolidation of the upper lobes of both lungs [76], and plural effusion [77].…”

“…Although the PICC provides the mainstay of long-term, stable venous access, its complications remain a concern. Peripherally inserted central catheter is associated with increased risks of catheter-related bloodstream infection [ 72 ], thrombosis [ 73 , 74 ], extravasation and intrahepatic collections of hyperalimentation [ 75 ], massive consolidation of the upper lobes of both lungs [ 76 ], and plural effusion [ 77 ]. From the unusual complications of PICC, an embolism of fragment of the catheter tip into the peripheral branch of the left pulmonary artery, perforation of the pulmonary artery peripheral branch [ 78 ], focal neurological manifestations in a form of tonic-clonic movement of the lower limb induced by inadvertent placement of PICC in the ascending lumber vein [ 79 ], oliguria due to malposition of the catheter tip into the renal vein with a subsequent vein occlusion or renal damage by solutions administered through the renal vein [ 80 ], cardiac arrythmia [ 81 ], cardiac tamponade, and death [ 82 , 83 ].…”

Research on the Design of Assistant Basketball Teaching System Based on Big Data

“…System development environment (SDE) is an application software used in response to the engineering development and maintenance of application software and system software based on basic hardware and digital software, which is called SDE. SDE is composed of software tools and environment integration mechanism [16,17]. Software tools are used to support software R & D processes, tasks, and activities.…”