J. Neurosci. Res. volume 87, issue 6, P1310-1322 2009 DOI: 10.1002/jnr.21952 View full text
Maria N. Mylonakou, Petur H. Petersen, Eric Rinvik, Aleksandra Rojek, Erla Valdimarsdottir, Sergey Zelenin, Thomas Zeuthen, Søren Nielsen, Ole P. Ottersen, Mahmood Amiry-Moghaddam

Abstract: AQP9 is an aquaglyceroporin that serves important functions in peripheral organs, including the liver. Reflecting the lack of AQP9 knockout mice, uncertainties still prevail regarding the localization and roles of AQP9 in the central nervous system. Here we present a comprehensive analysis of AQP9 gene expression in brain, based on a quantitative and multipronged approach that includes the use of animals with targeted deletion of the AQP9 gene. We show by real-time PCR that AQP9 mRNA concentration in rat and m…

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