Analysis of long-chain ω-3 fatty acid content in fish-oil supplements

Tatarczyk, Tobias; Engl, Julia; Ciardi, Christian; Laimer, Markus; Kaser, Susanne; Salzmann, Karin; Lenners, Ruth; Patsch, Josef R.; Ebenbichler, Christoph

doi:10.1007/s00508-007-0820-5

Cited by 19 publications

(19 citation statements)

References 29 publications

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“…The results of the current study lend support for the notion that an unacceptable level of inter-laboratory variability and errors in sample handling, analysis, and reporting could underlie the marked divergence in marine oil EPA/DHA content compliance that has been highlighted in recent reports 17–23, 28 . Possible cases of over-reporting of content may possibly also be noted in the literature 16, 35 . This suggests that laboratories meet significant and potentially overlooked technical challenges in making accurate fatty acid measurements in PUFA-rich oils in both directions.…”

Section: Discussionmentioning

confidence: 93%

Omega-3 Long-Chain Polyunsaturated Fatty Acid Content and Oxidation State of Fish Oil Supplements in New Zealand

Bannenberg¹,

Mallon

Edwards³

et al. 2017

Sci Rep

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Forty-seven fish oil products available on the New Zealand market were analyzed for eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) content, as well as for oxidative status in a collaborative effort by several analytical laboratories. Of the tested products, 72%, 86% and 77% complied with voluntary industry-set maximum limits on Peroxide Value (PV), para-Anisidine Value (p-AV), and TOTOX, respectively. 91% of the products complied with EPA/DHA content claims. All fish oils complied with a p-AV limit of 30, 98% with a PV limit of 10 meq O2/kg, and 96% with a calculated TOTOX value of 50, which are less stringent limits used by the European and British Pharmacopeia and the Australian authorities. The results are in stark contrast to the very low percentage of fish oil products reported to be in compliance with primary oxidation limits and EPA/DHA content by a recently published assessment of fish oil supplements in New Zealand. Possible reasons for this discrepancy are evaluated and discussed.

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Section: Discussionmentioning

confidence: 93%

Omega-3 Long-Chain Polyunsaturated Fatty Acid Content and Oxidation State of Fish Oil Supplements in New Zealand

Bannenberg¹,

Mallon

Edwards³

et al. 2017

Sci Rep

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“…Fish oils are rich sources of polyunsaturated fatty acids, especially docosahexaenoic acid and eicosapentaenoic acid [20,21], which are highly unsaturated fatty acids and are easily attacked by oxygen-containing free radicals. The free radical chain reaction is widely known as a common mechanism of lipid oxidation, which leads to deterioration and off-flavors in oils [22].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant capacity of robust polyaniline–ethyl cellulose films

Hsu

Kilmartin

2012

Reactive and Functional Polymers

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“…In a recent study17 in Belgium, 15 food supplements formulated as soft capsules containing n-3 fatty acids were evaluated by desegregation, determination of peroxide values and assay of the n-3 fatty acid content. All the products contained purified fish oil rich in n-3 fatty acids, mainly EPA and DHA, and were available as triglycerides, ethyl esters or free fatty acids.…”

Section: Introductionmentioning

confidence: 99%

Analysis of omega-3 fatty acid content of South African fish oil supplements

Opperman

Marais

Benadé

2011

Cardiovascular Journal of Africa

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IntroductionSubstantial evidence describes the protective effects of marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFA) on cardiovascular diseases as well as many other conditions. Numerous fatty acid preparations are marketed for supplementing the Western diet, which is low in n-3 fats. Since these preparations may vary in their n-3 PUFA content, we tested 45 commercially available products on the South African market for their fatty acid composition.MethodForty-five commercially available n-3 fatty acid supplements were analysed using gas–liquid chromatography to determine their fatty acid content.ResultsMore than half of the n-3 supplements available on the South African market contained ≤ 89% of the claimed content of EPA and/or DHA as stated on the product labels. To meet ISSFAL’s recommendation of 500 mg EPA + DHA/day can cost consumers between R2 and R5 per person per day (R60 to R150 p/p/month). Regarding rancidity, the majority of capsules contained conjugated diene (CD) levels higher than that of vegetable oil obtained from opened containers (three months) used for domestic cooking purposes, despite the addition of vitamin E as antioxidant.ConclusionSince no formal regulatory structure for dietary supplements currently exists in South Africa, consumers depend on self-regulation within the nutraceutical industry for assurance of product quality, consistency, potency and purity. Our results indicate that more than half of the n-3 fatty acid supplements on the South African market do not contain the claimed EPA and/or DHA contents as stated on product labels, and they contained CD levels higher than that in unused vegetable oils obtained from opened containers used for domestic cooking purposes.

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Analysis of long-chain ω-3 fatty acid content in fish-oil supplements

Abstract: Administering long-chain omega-3 fatty acid preparations may result in huge differences in terms of the actual amount ingested. It is therefore advisable to use the most standardized and purified products available.

Cited by 19 publications

References 29 publications

Omega-3 Long-Chain Polyunsaturated Fatty Acid Content and Oxidation State of Fish Oil Supplements in New Zealand

Omega-3 Long-Chain Polyunsaturated Fatty Acid Content and Oxidation State of Fish Oil Supplements in New Zealand

Antioxidant capacity of robust polyaniline–ethyl cellulose films

Analysis of omega-3 fatty acid content of South African fish oil supplements

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