In this chapter, the authors discuss the leadership in e-commerce security involves navigating the dynamic landscape of digital threats while fostering innovation. To being successful in leadership management over controlling the risk and providing an innovation on e-commerce field, it should mainly focus on security and threats. The discussion mainly addresses several technologies and methods available in AI, machine learning, and blockchain to enhance security measures. Also, it focuses on balancing risk management and ensures effective and balancing e-commerce platforms, for building trust and sustainable business growth.