Analysis by GC-MS of the hexane extract of the aerial parts ofAristolochia acutifolia Duchtr.

Abstract

Qualitative analysis by GC–MS of the three non‐polar fractions from the hexane extract of Aristolochia acutifolia Duchtr. was carried out and 47 constituents were identified. The major groups of constituents identified away these fractions were sesquiterpenes (spathulenol, 23.1%; β‐bisabolene, 9.0%; α‐eudesmol, 6.9%; α‐selinene, 5.2%; and trans‐α‐bergamotene, 5.1%), esters (ethyl hexadecanoate, 23.0%; ethyl 9‐octadecenoate, 11.6%; and methyl hexadecanoate, 7.9%), phenylpropanoids (myristicin, 35.3%; and elemicin, 15.8%), carboxilic acids (oleic, 22.8%; and palmitic acids, 20.3%), and n‐alkanes (pentadecane, 11.7%). Some constituents identified are described for the first time in this genus. Copyright © 2001 John Wiley & Sons, Ltd.

Terpenoids of Aristolochia and their biological activities

“…These two reports revealed that the A. triangularis is a rich source of entkaurane diterpenes. A diterpene (−)-kaur-16-ene 215 was also found in the essential oils of A. acutifolia, 125 A. argentina 119 and A. chilensis. 142 Lopes et al 195 reported the ent-kaurane-16␣,17diol 225 from A. pubescens, which was previously isolated from A. triangularis.…”

“…Two monoterpenoids, geranylacetone 7 and ␣-terpineol 14 were identified as minor constituents in the hexane extract of the aerial parts of A. acutifolia. 125 Similarly, monoterpenes constitute a small percentage of the essential oils obtained from the leaves, stems and roots of A. elegans. 126 Nineteen monoterpenes were identified in the essential oils of leaves and stems of A. gibertii.…”

“…The major types of sesquiterpenoids that have been found in the Aristolochia species include cadinanes, aristolanes, germacranes and bicyclogermacranes (Table 4). Palmeira et al 125 carried out a qualitative analysis of the three non polar fractions from the hexane extract of A. acutifolia by GC-MS and forty seven constituents were identified. In all the fractions analyzed, the sesquiterpenes: ␤bisabolene 52, ␣-selinene 107, ␣-eudesmol 113, spathulenol 158 and ␣-trans-bergamotene 172 were the most abundant.…”

Terpenoids of Aristolochia and their biological activities

“…These two reports revealed that the A. triangularis is a rich source of entkaurane diterpenes. A diterpene (−)-kaur-16-ene 215 was also found in the essential oils of A. acutifolia, 125 A. argentina 119 and A. chilensis. 142 Lopes et al 195 reported the ent-kaurane-16␣,17diol 225 from A. pubescens, which was previously isolated from A. triangularis.…”

“…Two monoterpenoids, geranylacetone 7 and ␣-terpineol 14 were identified as minor constituents in the hexane extract of the aerial parts of A. acutifolia. 125 Similarly, monoterpenes constitute a small percentage of the essential oils obtained from the leaves, stems and roots of A. elegans. 126 Nineteen monoterpenes were identified in the essential oils of leaves and stems of A. gibertii.…”

“…The major types of sesquiterpenoids that have been found in the Aristolochia species include cadinanes, aristolanes, germacranes and bicyclogermacranes (Table 4). Palmeira et al 125 carried out a qualitative analysis of the three non polar fractions from the hexane extract of A. acutifolia by GC-MS and forty seven constituents were identified. In all the fractions analyzed, the sesquiterpenes: ␤bisabolene 52, ␣-selinene 107, ␣-eudesmol 113, spathulenol 158 and ␣-trans-bergamotene 172 were the most abundant.…”

Terpenoids of Aristolochia and their biological activities

“…These two reports revealed that the A. triangularis is a rich source of entkaurane diterpenes. A diterpene (−)-kaur-16-ene 215 was also found in the essential oils of A. acutifolia, 125 A. argentina 119 and A. chilensis. 142 Lopes et al 195 reported the ent-kaurane-16␣,17diol 225 from A. pubescens, which was previously isolated from A. triangularis.…”

“…Two monoterpenoids, geranylacetone 7 and ␣-terpineol 14 were identified as minor constituents in the hexane extract of the aerial parts of A. acutifolia. 125 Similarly, monoterpenes constitute a small percentage of the essential oils obtained from the leaves, stems and roots of A. elegans. 126 Nineteen monoterpenes were identified in the essential oils of leaves and stems of A. gibertii.…”

“…The major types of sesquiterpenoids that have been found in the Aristolochia species include cadinanes, aristolanes, germacranes and bicyclogermacranes (Table 4). Palmeira et al 125 carried out a qualitative analysis of the three non polar fractions from the hexane extract of A. acutifolia by GC-MS and forty seven constituents were identified. In all the fractions analyzed, the sesquiterpenes: ␤bisabolene 52, ␣-selinene 107, ␣-eudesmol 113, spathulenol 158 and ␣-trans-bergamotene 172 were the most abundant.…”

Terpenoids of Aristolochia and their biological activities

“…These two reports revealed that the A. triangularis is a rich source of entkaurane diterpenes. A diterpene (−)-kaur-16-ene 215 was also found in the essential oils of A. acutifolia, 125 A. argentina 119 and A. chilensis. 142 Lopes et al 195 reported the ent-kaurane-16␣,17diol 225 from A. pubescens, which was previously isolated from A. triangularis.…”

“…Two monoterpenoids, geranylacetone 7 and ␣-terpineol 14 were identified as minor constituents in the hexane extract of the aerial parts of A. acutifolia. 125 Similarly, monoterpenes constitute a small percentage of the essential oils obtained from the leaves, stems and roots of A. elegans. 126 Nineteen monoterpenes were identified in the essential oils of leaves and stems of A. gibertii.…”

“…The major types of sesquiterpenoids that have been found in the Aristolochia species include cadinanes, aristolanes, germacranes and bicyclogermacranes (Table 4). Palmeira et al 125 carried out a qualitative analysis of the three non polar fractions from the hexane extract of A. acutifolia by GC-MS and forty seven constituents were identified. In all the fractions analyzed, the sesquiterpenes: ␤bisabolene 52, ␣-selinene 107, ␣-eudesmol 113, spathulenol 158 and ␣-trans-bergamotene 172 were the most abundant.…”