ANÁLISE DO PERFIL FITOQUÍMICO DE Tripodanthus acutifolius (RUIZ &amp; PAVÓN) TIEGHEM, LORANTHACEAE

Grüner, Juliana Maria; Souza, Thaís Klein de; Benitez, Lisianne Brittes; Silva, Chana de Medeiros da

doi:10.17058/rjp.v0i1.2860

“…Estes resultados assemelham-se com os nossos para os extratos de pétalas de rosa, girassol e calêndula elaborados com álcool à frio pelo método convencional do presente estudo e percentual do extrato hexânico de 3,7%, resultado inferior aos encontrados pelo método convencional utilizando álcool à frio como solvente para elaborar extratos das pétalas desse estudo. Grüner et al (2012) ao elaborarem extratos aquosos e metanólicos das folhas de erva-de-passarinho (Tripodanthus acutifolius) através da técnica de maceração ( 24horas), obtiveram rendimentos de 30 g de extrato aquoso bruto (rendimento de 30%), e 20 g de extrato metanólico bruto (rendimento de 20%). A água, por ser um solvente de amplo espectro é capaz de extrair um maior número de compostos do que o metanol.…”

Section: Resultsunclassified

Identificação, Caracterização, Quantificação E Tratamento De Resíduos Sólidos Em Indústria De Beneficiamento De Arroz Localizada Em Barreiras - Ba

Almeida¹,

Souza²,

Prado³

et al. 2019

Avanços E Desafios Da Nutrição 4

0

View full text Add to dashboard Cite

show abstract

“…Phytochemical studies of T. acutifolius revealed the presence of several phenolic acids, hydroxycinnamic acids, tannins, flavonoids, and tripodantosides [30][31][32]. Apaza et al [33] suggested that (E)-2',4'-dihydroxy-6'-methoxy-chalcone, 6,2',4'-trimethoxyflavone, 5,3',4'-trihydroxy-6,7,8-trimethoxyflavone, and 5,4'-dihydroxy-6,7,8-trimethoxyflavone were the main compounds responsible for the anti-inflammatory action of T. acutifolius.…”

Section: Introductionmentioning

confidence: 99%

Anti-inflammatory and Anti-arthritic Activities of Aqueous Extract and Flavonoids from Tripodanthus acutifolius Leaves in Mice Paw Oedema

Ticona

¹

,

Serban

²

,

Ticona³

et al. 2021

Planta Medica International Open

View full text Add to dashboard Cite

Tripodanthus acutifolius, commonly known as Jamillo, is an herbal remedy used in traditional Andean medicine to treat joint problems, such as sprains, dislocations, and rheumatic pain. This study aimed to evaluate the in vitro and in vivo anti-inflammatory and anti-arthritic activity of the aqueous extract and isolated compounds of T. acutifolius. A bioguided phytochemical analysis based on NMR/MS was performed to identify the compounds of the aqueous extract from T. acutifolius. The anti-inflammatory and anti-arthritic activity were evaluated by measuring inflammatory parameters (TNF-α, C-reactive protein, and fibrinogen) in murine models. The chemical structure determination led to the identification of four flavonoids: (E)-2’,4’-dihydroxy-6’-methoxy-chalcone (1), 6,2’,4’-trimethoxyflavone (2), 5,3’,4’-trihydroxy-6,7,8-trimethoxyflavone (3), and 5,4’-dihydroxy-6,7,8-trimethoxyflavone (4). All compounds inhibited the production of TNF-α in the RAW 264.7 cell line, with IC50 values of 0.78, 1.43, 5.73, and 9.71 μM, respectively. In addition, all flavonoids decreased the levels of TNF-α, C-reactive protein, and fibrinogen at a concentration of 5 mg/kg in murine models. Our research shows that these compounds isolated from T. acutifolius have anti-inflammatory and anti-arthritic properties, providing scientific evidence for the traditional use of this plant species.

show abstract

“…Phytochemical studies of T. acutifolius revealed the presence of several phenolic acids, hydroxycinnamic acids, tannins, flavonoids, and tripodantosides [30][31][32]. Apaza et al [33] suggested that (E)-2',4'-dihydroxy-6'-methoxy-chalcone, 6,2',4'-trimethoxyflavone, 5,3',4'-trihydroxy-6,7,8-trimethoxyflavone, and 5,4'-dihydroxy-6,7,8-trimethoxyflavone were the main compounds responsible for the anti-inflammatory action of T. acutifolius.…”

Section: Introductionmentioning

confidence: 99%

Untitled

2021

Planta Medica International Open

0

View full text Add to dashboard Cite

show abstract

ANÁLISE DO PERFIL FITOQUÍMICO DE Tripodanthus acutifolius (RUIZ & PAVÓN) TIEGHEM, LORANTHACEAE

Cited by 3 publications

References 9 publications

Identificação, Caracterização, Quantificação E Tratamento De Resíduos Sólidos Em Indústria De Beneficiamento De Arroz Localizada Em Barreiras - Ba

Identificação, Caracterização, Quantificação E Tratamento De Resíduos Sólidos Em Indústria De Beneficiamento De Arroz Localizada Em Barreiras - Ba

Anti-inflammatory and Anti-arthritic Activities of Aqueous Extract and Flavonoids from Tripodanthus acutifolius Leaves in Mice Paw Oedema

Untitled

Contact Info

Product

Resources

About