Anaemia and low birth weight in Medani, Hospital Sudan

Elhassan, Elhassan M.; Abbaker, Ameer O; Haggaz, Abderahuim D.; Abubaker, Magid S; Adam, Ishag

doi:10.1186/1756-0500-3-181

Cited by 57 publications

(61 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This could explain recent findings at the same hospital, where anemic women were at nine times the risk of LBW delivery [2] and 45% of antenatal attendees had zinc deficiency [19]. The finding of a low zinc level in LBW deliveries is in agreement with recent reports from developing countries, such as Tanzania [14] and India [15].…”

Section: Discussionsupporting

confidence: 87%

Zinc and copper levels in low birth weight deliveries in Medani Hospital, Sudan

et al. 2014

Self Cite

View full text Add to dashboard Cite

BackgroundLow birth weight (LBW) is a worldwide health problem, especially in developing countries. We conducted a case–control study at Medani Hospital, Sudan. Cases were women who delivered a LBW (<2500 g) newborn and consecutive women who delivered a normal weight (>2500 g) newborn were controls. Questionnaires were used to collect clinical data. Zinc and copper levels were measured by an atomic absorption spectrophotometer.FindingsThe two groups (50 in each arm) were well matched in their basic characteristics. Median (25–75th interquartile range) maternal zinc (62.9 [36.3–96.8] vs. 96.2 [84.6–125.7] μg/dl; P <0.001) and copper (81.6 [23.7–167.5] vs. 139.8 [31.9–186.2] μg/dl; P = 0.04) levels were significantly lower in cases than in controls. Cord copper levels in cases were significantly lower than those in controls (108 [55.1–157.9] vs. 147.5 [84.5–185.2] μg/dl; P = 0.02). There were significant direct correlations between birth weight and maternal copper levels and maternal and cord zinc levels.ConclusionsMaternal zinc and copper levels, as well as cord copper levels, are lower in LBW newborns than in those with normal weight.

show abstract

Section: Discussionsupporting

confidence: 87%

Zinc and copper levels in low birth weight deliveries in Medani Hospital, Sudan

et al. 2014

Self Cite

View full text Add to dashboard Cite

show abstract

“…The aim of this study was to build upon the previous work on placental malaria and LBW in Sudan [23-25]; specifically, to investigate the effect of submicroscopic levels of malaria parasites during pregnancy on birth weight. The study took place in the Medani Maternity Hospital in Central Sudan.…”

Section: Introductionmentioning

confidence: 99%

Submicroscopic Plasmodium falciparum malaria and low birth weight in an area of unstable malaria transmission in Central Sudan

Mohammed

Salih

Elhassan

et al. 2013

Malar J

Self Cite

View full text Add to dashboard Cite

BackgroundMalaria, which frequently occurs in pregnant women in the tropics, is a leading cause of maternal anaemia and low birth weight (LBW) in infants. Few data exist concerning malaria infections that are present at submicroscopic levels during pregnancy and their LBW delivery in babies.MethodsA case–control study (87 in each group) was conducted at the Medani Hospital, Central Sudan. Cases were women who had LBW deliveries where the infants weighed < 2,500 g. Controls were parturient women without having LBW babies. Obstetrical and medical characteristics were gathered from both groups through structured questionnaires. Both cases and controls were investigated for malaria using microscopic blood film analysis, placental histology and polymerase chain reaction (PCR). Microscopic and PCR analyses were conducted on maternal peripheral blood, placenta, and umbilical cord samples. Infant weights were recorded immediately after birth.ResultsPlasmodium falciparum-positive blood films were not obtained from any of the women (cases or controls). Twenty-seven (31.0%) versus 22 (25.3%) (P = 0.500) of the cases and controls, respectively, had placental malaria infections as determined by histological examination. In comparison to the controls, the submicroscopic malaria infection prevalence rates were significantly higher in the cases; 24 (27.6%) vs six (7.0%), P < 0.001. Multivariate analysis showed that while malaria infection of the placenta (based on histology) was not associated with LBW, submicroscopic P. falciparum infection (OR = 6.89, 95% CI = 2.2–20.8; P = 0.001), or a combination of histologically determined and submicroscopic infections (OR = 2.45, 95% CI = 1.2–4.9; P = 0.012), were significantly associated with LBW.ConclusionIn Central Sudan, pregnant women were at a higher risk of having an LBW delivery if they had submicroscopic infections rather than a histological diagnosis of placental malaria.

show abstract

“…The goal of “A World Fit for Children” sought to reduce the incidence of LBW of infants by at least one-third over 10 years, of which the deadline was 2010. The reduction in LBW of infants is also an important objective of Millennium Development Goal (MDG) 4, which seeks to reduce child mortality by two-thirds by 2015[6].…”

Section: Introductionmentioning

confidence: 99%

Maternal risk factors for low birth weight for term births in a developed region in China: a hospital-based study of 55,633 pregnancies

Bian¹,

Zhang²,

Li³

et al. 2013

J Biomed Res

View full text Add to dashboard Cite

Low birth weight (LBW) is an important risk factor for neonatal and infant mortality and morbidity in adults.. However, no large scale study on the prevalence of LBW and related maternal risk factors in China has been published. To explore the effects of maternal factors on LBW for term birth in China, we conducted a hospital-based retrospective study of 55, 633 Chinese pregnancy cases between 2001 and 2008. Maternal sociodemographic data, history of infertility and contraceptive use were obtained. Their medical status and diseases during pre-pregnancy were examined by physical examination at the first antenatal care visit. Maternal medical status before childbirth and pregnancy outcomes, including body weight, infant gender, multiple pregnancy and congenital anomalies, were recorded. Univariate and multivariate logistic regression, and linear regression were used to investigate the relationship between maternal factors and term LBW. The general incidence of term LBW was 1.70% in the developed area of China. After preliminary analysis using the univariate model, low primary education, anemia, hypertensive disorders, placental previa, oligohydramnios and premature rupture of membrane were predicted as independent factors of term LBW in the multivariate model. Furthermore, the decrease in annual frquencies of these risk factors were major causes of gradual decline in the incidence of LBW (from 2.43% in 2001 to 1.21% in 2008). The study demonstrated that among maternal factors, primary education, anemia and hypertensive disorders could contribute to LBW for term birth even in the most developed area of China.

show abstract

Anaemia and low birth weight in Medani, Hospital Sudan

Cited by 57 publications

References 22 publications

Zinc and copper levels in low birth weight deliveries in Medani Hospital, Sudan

Zinc and copper levels in low birth weight deliveries in Medani Hospital, Sudan

Submicroscopic Plasmodium falciparum malaria and low birth weight in an area of unstable malaria transmission in Central Sudan

Maternal risk factors for low birth weight for term births in a developed region in China: a hospital-based study of 55,633 pregnancies

Contact Info

Product

Resources

About