2009
DOI: 10.1097/moo.0b013e32832ac393
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Abstract: Rhinosinusitis is a common medical problem that interferes with patient quality of life and loss of work productivity. Because of the heterogeneity that underlies its pathology, no one treatment regimen exists for the management of rhinosinusitis.

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Cited by 80 publications
(65 citation statements)
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“…Rhinosinusitis is a disease that is heterogeneous in its clinical and pathological manifestations, interfering with patients' quality of life and resulting in missed work and lost productivity therefore imposing a significant economic burden [6].…”
Section: Discussionmentioning
confidence: 99%
“…Rhinosinusitis is a disease that is heterogeneous in its clinical and pathological manifestations, interfering with patients' quality of life and resulting in missed work and lost productivity therefore imposing a significant economic burden [6].…”
Section: Discussionmentioning
confidence: 99%
“…umerous studies have demonstrated the value of saline irrigations for patients with chronic rhinosinusitis (CRS), [1][2][3] but only limited research addresses the best means of delivering irrigation to sinonasal mucosa. Compelling evidence exists that nasal douching is more effective at providing gross topical coverage of sinus mucosa than spray or nebulizers.…”
mentioning
confidence: 99%
“…In the United States, the health burden of CRS is further complicated by its high prevalence, estimated to be about 14% to 16%, with no predilection for age or gender [3••]. Symptomatic complaints of CRS result in 18 to 22 million annual visits to outpatient facilities, totaling $5.8 billion in annual healthcare costs for the diagnosis, treatment, and management of the disorder [4,5].…”
Section: Introductionmentioning
confidence: 99%