An update on plexiform fibrohistiocytic tumor and addition of 66 new cases from the Armed Forces Institute of Pathology, in honor of Franz M. Enzinger, MD

Differential gene expression profiles of neurothekeomas and nerve sheath myxomas by microarray analysis

“…Taken together, all these features have led some authors to suggest that neurothekeomas and plexiform fibrohistiocytomas are the same lesion. 89,90 It has been suggested that the deeper subcutaneous location of plexiform fibrous histiocytomas is responsible for the higher rates of local recurrence and rare instances of metastases. 24,[87][88][89][90] With one exception, the cases of plexiform fibrous histiocytomas seen at our institution during the study were outside consultations for which we were not able to obtain material for testing.…”

Plexiform fibrohistiocytic tumor in the submandibular region: A rare diagnosis

“…PFHT is an uncommon mesenchymal tumor in children and young adults [2], more frequent in females and mostly (April-June 2010) 62(2): [189][190] occurs in the upper extremity followed by lower extremity and head and neck region [4,5]. Since it was first described in 1988 [1] there have been few series [4][5][6] and many single case reports in literature.…”

“…Since it was first described in 1988 [1] there have been few series [4][5][6] and many single case reports in literature. We present a rare case in a male patient presenting in the submandibular region.…”

Plexiform Leiomyoma of the Soft Palate: A Case Study and Literature Review

“…Morphological features of a plexiform neurofibroma with an immunoreactivity profile for desmin and smooth muscle actin produces a rare variant of a benign plexiform lesion called plexiform leiomyoma. Plexiform leiomyoma's presence has only been documented in the uterus and esophagus [1][2][3][4][5][6][7][8][9][10][11]. The following case study demonstrates the first ever finding of a plexiform leiomyoma outside the gastrointestinal tract and uterus located on the soft palate.…”

“…Plexiform arrangement may suggest lesions which are spindled and focally show some whorling and fascicular pattern [1]. Literature has provided a vast differential diagnosis of plexiform lesion some of which include schwannoma, fibrohistiocytic tumors, angiomyxoid tumors, fibromyxoma [2][3][4][5]. Plexiform neurofibroma is another plexiform tumor shown to have predilection for the head and neck region.…”