An Unusual Orthopaedic Disease: Sarcoidosis—A Case Report

Abstract

Sarcoidosis is an idiopathic, noncaseating granulomatous disorder with wide systemic involvement. It is encountered widely around the world and it affects both sexes, all the races in all age groups. Lungs, eyes, and skin are the organs most commonly affected. Constitutional features such as weight loss, fatigue, and myalgia are the most common symptoms. Bone involvement, which is very rare, was reported as present in 3 to 13% of effected cases, and it is most commonly seen in hands and feet, compared with long bone involvement, which is extremely rare. We hereby present a case with a diagnosis of sarcoidosis and multiple bone involvement emphasizing the importance of differential diagnosis.

Frontal swelling – An unusual presentation of sarcoidosis: A case report

“…[6] CT scan of skull identifies sarcoid lesions as regions of enhanced uptake in subcutaneous area with areas of bone destruction and sclerosis. [7,8] MRI findings are high-intensity signals in T2weighted images. [8] However, in our patient, these imaging modalities were inconclusive and histopathology revealed the typical sarcoidal granulomas.…”

“…[7,8] MRI findings are high-intensity signals in T2weighted images. [8] However, in our patient, these imaging modalities were inconclusive and histopathology revealed the typical sarcoidal granulomas.…”

“…Bone sarcoidosis was described by Kreibich for the 1 st time in 1904. [8] Even though, the disease most commonly affects hands and feet, other sites such as axial skeleton, skull, long bones, and ribs may also be affected occasionally. e diagnosis is often difficult since the disease when manifests as lytic lesions, may mimic metastasis or myeloma.…”

Osseous manifestations of sarcoidosis

“…It has been suggested that bone cysts are more common in black people [24]. Various locations of sarcoidosis within the bone have different presentations, including apple core pattern in the finger [25], and different X-ray pictures in the long bones [26][27][28][29]. In some patients, bone lesions are described as having a "moth-eaten" pattern involving the cortex of the phalanges and accompanied by soft tissue swelling.…”