An unmatched case controlled study of clinicopathologic abnormalities in dogs with Bartonella infection

Concurrent Bartonella henselae infection in a dog with panniculitis and owner with ulcerated nodular skin lesions

“…berkhoffii . For unknown reasons, as occurred in this dog and owner, a subset of B. henselae ‐infected dogs and people remain B. henselae seronegative by immunofluorescence antibody testing . Failure to detect B. henselae antibodies may reflect antibody‐negative (anergy) occult, host‐adapted chronic infection, variation in antibody reactivity among strains of a Bartonella sp.…”

Hyperinsulinemic Hypoglycemia Syndrome in 2 Dogs with Bartonellosis

“…bacteremia are often normal, eosinophilia, lymphocytosis, monocytosis, thrombocytopenia, thrombocytosis, and hypogammglobulinemia occurs in a subset of dogs with serological or BAPGM enrichment blood culture/PCR evidence of Bartonella sp. infections 9, 10, 11. Because B. henselae was amplified and sequenced from postantibiotic blood of dog 1, paraffin‐embedded tissues from dog 2 were tested retrospectively, resulting in successful PCR amplification and sequencing of B. koehlerae DNA.…”

Prostatitis, Steatitis, and Diarrhea in a Dog following Presumptive Flea-Borne Transmission of Bartonella henselae

“…For reasons that remain incompletely understood, approximately three quarters of B. henselae-infected dogs (PCR positive from blood, tissues, or BAPGM enrichment blood or tissue culture) do not have detectable B. henselae antibodies by IFA testing (5,12,13). Therefore, IFA serological diagnosis of bartonellosis currently lacks sensitivity, for reasons that in part remain unclear.…”

“…In a case-control study, weight loss was significantly associated with Bartonella infections in dogs (5). Although anemia, thrombocytopenia, thrombocytosis, eosinophilia, and monocytosis (this dog) occur in association with canine bartonellosis, a lack of hematological and biochemical changes is not unusual, despite a severe progressive course of illness (5,6). As diarrhea has not been reported as a distinct clinical entity in dogs infected with Bartonella spp., the colonic diarrhea, eosinophilic enteritis, and weight loss in this dog may have been secondary to the regional abdominal inflammation or another undetermined infectious or noninfectious cause.…”

“…In a case-control study, weight loss was significantly associated with Bartonella infections in dogs (5). Although anemia, thrombocytopenia, thrombocytosis, eosinophilia, and monocytosis (this dog) occur in association with canine bartonellosis, a lack of hematological and biochemical changes is not unusual, despite a severe progressive course of illness (5,6).…”