2003
DOI: 10.1016/s0161-6420(02)01643-3
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An outbreak of Mycobacterium chelonae infection after LASIK

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Cited by 133 publications
(107 citation statements)
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References 90 publications
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“…Unsatisfactory medical therapy, can be associated with a delayed diagnosis, slow response to therapy, inadequate drug penetration, resistance to most conventional antibiotics and the emergence of a resistant strain, especially when using monotherapy (3,5) . …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Unsatisfactory medical therapy, can be associated with a delayed diagnosis, slow response to therapy, inadequate drug penetration, resistance to most conventional antibiotics and the emergence of a resistant strain, especially when using monotherapy (3,5) . …”
Section: Discussionmentioning
confidence: 99%
“…More recently, mycobacteria species were reported to cause infectious keratitis after LASIK, photorefractive keratectomy, and radial keratectomy (4)(5) .…”
Section: Introductionmentioning
confidence: 99%
“…Hence, clinical characteristics of NTM infections are key for suspecting infection post LASIK. NTM keratitis is characterized by its indolent course and low antimicrobial response, progressing to a severe necrosis due to the inflammatory process (9,(19)(20) . Patients report pain, photophobia, decreased vision and redness, and alternatively they may complain of foreign body sensation or just a mild irritation (9) .…”
Section: Nonrandomized Experimentsmentioning
confidence: 99%
“…However, mycobacterial infections have been frequently associated with keratitis post LASIK due to failure in antimicrobial therapy, especially monotherapy (29) . Nevertheless some authors recommend performing cultures of corneal infiltrates to confirm the diagnosis and determine sensitivity to antibiotics to implement appropriate therapeutic measures (9,20) . Considering that the risk for infection represents an important threat to the safety of patients and professionals delivering care, prevention and control actions should be implemented in the entire organizational structure.…”
Section: Nonrandomized Experimentsmentioning
confidence: 99%
“…2 Gram-positive infections and mycobacterial infections were more likely to present less than 7 days and 10 or more days after LASIK, respectively. 1,2,13 Severe reductions in visual acuity were significant with fungal infections. 2 As LASIK increases in popularity, the incidence of post-LASIK infectious complications will also likely increase.…”
Section: Commentmentioning
confidence: 99%