An Outbreak of Mycobacterial Furunculosis Associated with Footbaths at a Nail Salon

Winthrop, Kevin; Abrams, Marcy; Yakrus, Mitchell A.; Schwartz, Ira; Ely, Janet; Gillies, Donald; Vugia, Duc J.

doi:10.1056/nejmoa012643

Cited by 193 publications

(130 citation statements)

References 13 publications

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“…These have included alcohol-tattoo ink contaminated with M. chelonae 368 and footbaths in nail salons contaminated with NTM spp. 369 Summary. Most potential sources of pathogens that have been identified in the healthcare environment can be eliminated by following facility processes for the cleaning and disinfection of surfaces and equipment.…”

Section: Iiid2 Healthcare Sources: Water Surfaces Equipment Airmentioning

confidence: 99%

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Saiman

Siegel

LiPuma

et al. 2014

Infect. Control Hosp. Epidemiol.

345

382

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The 2013 Infection Prevention and Control (IP&C) Guideline for Cystic Fibrosis (CF) was commissioned by the CF Foundation as an update of the 2003 Infection Control Guideline for CF. During the past decade, new knowledge and new challenges provided the following rationale to develop updated IP&C strategies for this unique population:1. The need to integrate relevant recommendations from evidence-based guidelines published since 2003 into IP&C practices for CF. These included guidelines from the Centers for Disease Control and Prevention (CDC)/Healthcare Infection Control Practices Advisory Committee (HICPAC), the World Health Organization (WHO), and key professional societies, including the Infectious Diseases Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA). During the past decade, new evidence has led to a renewed emphasis on source containment of potential pathogens and the role played by the contaminated healthcare environment in the transmission of infectious agents. Furthermore, an increased understanding of the importance of the application of implementation science, monitoring adherence, and feedback principles has been shown to increase the effectiveness of IP&C guideline recommendations.2. Experience with emerging pathogens in the non-CF population has expanded our understanding of droplet transmission of respiratory pathogens and can inform IP&C strategies for CF. These pathogens include severe acute respiratory syndrome coronavirus and the 2009 influenza A H1N1. Lessons learned about preventing transmission of methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant gram-negative pathogens in non-CF patient populations also can inform IP&C strategies for CF.

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Section: Iiid2 Healthcare Sources: Water Surfaces Equipment Airmentioning

confidence: 99%

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Saiman

Siegel

LiPuma

et al. 2014

Infect. Control Hosp. Epidemiol.

345

382

View full text Add to dashboard Cite

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“…In contrast, NTM infections in immunocompetent hosts are often localized, such as SSTIs. Healthcare-associated or postsurgical wound infections caused by RGM have often been reported as SSTIs [1,[5][6][7][8]. The clinical presentation includes cellulitis, abscess formation, draining sinuses, and postoperative wound infection.…”

Section: Discussionmentioning

confidence: 99%

“…The therapeutic drugs usually recommended for infections involving the M. fortuitum group include amikacin, cefoxitin, imipenem/cilastatin, and fluoroquinolones [13]. In a study of isolates from a large nail salon outbreak of SSTIs, 29 isolates were susceptible to amikacin (100%), ciprofloxacin (100%), minocycline (100%), cefoxitin (91%), doxycycline (89%), gentamicin (82%), and trimethoprimsulfamethoxazole (TMP-SMX) (61%), with intermediate susceptibility to clarithromycin (86%) [5,16]. However, a study from Taiwan reported a high prevalence of antimicrobial resistance in RGM including the M. fortuitum group (69 isolates), and amikacin was found to be the most active agent (100% susceptibility).…”

Section: Discussionmentioning

confidence: 99%

Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan

Tsai

Chen

Liao

et al. 2016

J Infect Dev Ctries

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Mycobacterium fortuitum group (M. fortuitum), also known as rapidly growing Mycobacteria, can cause pyogenic infections in human beings, most commonly in immunocompromised patients. Herein, we present a 40-year-old immunocompetent male patient who underwent planned excision of a sebaceous cyst in the abdominal wall. He suffered from tender erythematous lesions with purulent discharge around the healing wound that developed 2 weeks after surgery. Gram stain, bacterial and fungal culture results of the wound were negative. A diagnosis of nontuberculous mycobacteria was made from a wound culture from the area of operative debridement, which was subsequently confirmed to be M. fortuitum group using PCR-restriction fragment length polymorphism analysis of the hsp65 gene. The patient received 4 weeks of parenteral imipenem/cilastatin 500 mg every 6 hours and amikacin 500 mg every 12 hours, plus oral clarithromycin 500 mg twice daily, and the wound recovered completely. He was discharged and followed up regularly at our outpatient clinic, and continued taking oral ciprofloxacin and clarithromycin 500 mg twice daily for 6 months. This case highlights the importance of strict aseptic precautions even during minor procedures, and also the characteristics of M. fortuitum infections in immunocompetent patients, which usually develop as localized postsurgical wound infections. We also share our experience in successfully treating a M. fortuitum complicated skin and soft tissue infection.

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“…Se ha identifi cado al lavado de pies en lugares comunitarios durante un proceso de pedicuría, como un sitio de brote de forunculosis asociada a M. fortuitum 14,15 .…”

Section: Discussionunclassified

Infección protésica mamaria por Mycobacteriumfortuitum en una paciente con lupus eritematoso sistémico

Lizaso¹,

Garcı́a²,

Aguirre³

et al. 2011

Rev. chil. infectol.

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Breast implant infection by Mycobacterium fortuitum in a patient with systemic lupus erythematosusIn recent decades there has been an increase in the number of breast implants for reconstruction and cosmetic purposes. Infection is a severe complication mostly caused by Staphylococcus aureus or coagulase-negative staphylococci. Mycobacteria are an infrequent cause of infection in this type of surgery. We describe a case of Mycobacterium fortuitum infection in a patient with lupus, subjected to a prosthetic replacement. These patients are more prone to unusual opportunistic infections. Treatment always requires both removal of prosthetic material and antibiotic therapy.Key words: Breast implants; atypical mycobacterial infection; systemic lupus erythematosus; Mycobacterium fortuitum.Palabras clave: Implantes mamarios, infecciones por micobacterias atípicas, Mycobacterium fortuitum. Caso clínicoP aciente con 50 años de edad, con diagnóstico de lupus eritematoso sistémico (LES) hacía cuatro años. Durante su evolución presentó como intercurrencia un síndrome antifosfolipídico y nefritis lúpica que requirió tratamiento con anticoagulantes orales, azatioprina 100 mg/día, hidroxicloroquina 200 mg/día y prednisona 20 mg/día en dosis decreciente. En el año 1996 se le practicó una mastectomía bilateral por antecedentes familiares directos de neoplasia mamaria y hallazgos mamográfi cos de micro-calcifi caciones agrupadas en ambas mamas. Con diagnóstico histopatológico de displasia severa se procedió a la colocación de prótesis mamarias texturizadas por vía submuscular. En agosto de 2008 fue sometida a un recambio protésico mamario bilateral, por encapsulamiento y retracción cutánea, colocándose prótesis texturizadas por vía retromuscular con incisión inframamaria. Al mes del procedimiento, comenzó con equivalentes febriles, tumefacción y eritema en ambas mamas. Se realizó una ecografía de tejidos blandos que demostró una colección periprotésica derecha evidente y mínima contralateral. Se le indicó reposo, hielo y anti-infl amatorios. Luego de una mejoría transitoria recrudeció el cuadro por lo que se le prescribió amoxicilina/ác. clavulánico (3 gr/ día) que luego fue modifi cado a ciprofl oxacina asociada a clindamicina. Posteriormente, consultó a un médico infectólogo quien le aconsejó retiro de ambas prótesis mamarias dado el hallazgo ecográfi co de colecciones bilaterales; sin embargo, la paciente no accedió. Evolucionó posteriormente con drenaje espontáneo de secreción en la mama derecha, por lo que se realizó una evacuación quirúrgica, obteniéndose un líquido de aspecto citrino que se envió a cultivo (Figuras 1 y 2).

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An Outbreak of Mycobacterial Furunculosis Associated with Footbaths at a Nail Salon

Abstract: We identified a large outbreak of rapidly growing mycobacterial infections among persons who had had footbaths and pedicures at one nail salon. Physicians should suspect this cause in patients with persistent furunculosis after exposure to whirlpool footbaths.

Cited by 193 publications

References 13 publications

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update

Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan

Infección protésica mamaria por Mycobacteriumfortuitum en una paciente con lupus eritematoso sistémico

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