2011
DOI: 10.1590/s0102-86502011000700008
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Abstract: PURPOSE: Development of an improved animal model for studying skin burns in rats. METHODS: Twenty-four male Wistar rats were randomly assigned to four groups (n=6): G1-Control, G2-T100°C, G3-T150°C and G4-T200°C. Two 10 x 10 mm squares were outlined with a sterile surgical marker on each side and along the vertebral column using a prepared template positioned between the anterior and posterior limbs. G2-G4 rats were subjected to 100°C, 150°C and 200ºC thermal burns, respectively. G1 rats served as controls. Bu… Show more

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Cited by 34 publications
(26 citation statements)
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“…Our results concerning burned skin wound depth and healing phases are comparable to prior works [24][25][26].…”
Section: Discussionsupporting
confidence: 90%
“…Our results concerning burned skin wound depth and healing phases are comparable to prior works [24][25][26].…”
Section: Discussionsupporting
confidence: 90%
“…The dorsal skin was surgically prepared with successive applications of 2% chlorhexidine scrub. A previously described model [19][20] …”
Section: Burnsmentioning
confidence: 99%
“…Since the mid-20 th century, owing to numerous experimental or clinical studies, treatment modalities have been improved. However, due to ethics and standardization problems in clinical studies, experimental studies have been mostly preferred for physiopathology and healing procedures (3)(4)(5)(6)(7)(8)(9). Therefore, various scalding and contact burn models have been defined (3,(10)(11)(12)(13)(14).…”
Section: Introductionmentioning
confidence: 99%