Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

1
19
0

Year Published

2012
2012
2024
2024

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 21 publications
(20 citation statements)
references
References 25 publications
1
19
0
Order By: Relevance
“…PF-8 degrades PARP-1 in a proteasome-dependent way. Several studies have reported the association of proteasome activity with PARP-1 degradation (28)(29)(30). To investigate whether PF-8 induces the degradation of PARP-1 in a proteasome-dependent manner, HEK293T cells transfected with increasing amounts of PF-8 for 18 h were treated with the 26S proteasome subunit inhibitor MG132 (1 M) (31) (Fig.…”
Section: Resultsmentioning
confidence: 99%
“…PF-8 degrades PARP-1 in a proteasome-dependent way. Several studies have reported the association of proteasome activity with PARP-1 degradation (28)(29)(30). To investigate whether PF-8 induces the degradation of PARP-1 in a proteasome-dependent manner, HEK293T cells transfected with increasing amounts of PF-8 for 18 h were treated with the 26S proteasome subunit inhibitor MG132 (1 M) (31) (Fig.…”
Section: Resultsmentioning
confidence: 99%
“…3T3-L1 preadipocytes were purchased from RIKEN Bioresource Center (Ibaraki, Japan) and were maintained in Dulbecco's modified Eagle's medium (low glucose) (Wako, 041–29775) with 10% fetal bovine serum and 1% penicillin/streptomycin (Sigma) 55,56 . Differentiation of 3T3-L1 preadipocytes to adipocytes was performed as previously reported by our laboratory 55,56 …”
Section: Methodsmentioning
confidence: 99%
“…pMXs-neo-mU6 vector was constructed as previously reported 55,56 . We designed a mouse Ctsl shRNA expression vector based on target sequences for effective CTSL protein knockdown, also as previously reported 56 .…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…In fact, a number of MDM2-targeting compounds have been identified or designed, which accounts for the majority of the current E3-liagse-targeting molecules [134]. Nutlin is the first selective small molecule that specifically targets MDM2-p53 interaction [135]. Crystal structure analysis revealed that Nutlin interacts with a region in p53, which MDM2 also utilizes to bind with the p53 protein [136].…”
Section: Small Molecules Target the Ubiquitin-proteasome Systemmentioning
confidence: 99%