An interpenetrating glass-thermosensitive hydrogel construct

Gu, Yuandong; Dhanarajan, Anish P.; Hruby, Sarah L.; Baldi, Antonio; Ziaie, Babak; Siegel, Ronald A.

doi:10.1016/j.snb.2009.02.044

Cited by 6 publications

(5 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Instead, it operates by ''playing off'' gradients in pressure, BaCl 2 concentration, and free crown ether concentration. Gu et al [46,47] provide another example involving the interplay of gradients. In this system, shown in Figure 10.1a, a cross-linked pNIPA hydrogel is polymerized in a crosscut glass wafer.…”

Section: Thermofluidic Oscillatormentioning

confidence: 99%

Oscillatory Systems Created with Polymer Membranes

Siegel¹

2010

Nonlinear Dynamics With Polymers

Self Cite

View full text Add to dashboard Cite

Section: Thermofluidic Oscillatormentioning

confidence: 99%

Oscillatory Systems Created with Polymer Membranes

Siegel¹

2010

Nonlinear Dynamics With Polymers

Self Cite

View full text Add to dashboard Cite

“…NIPA based polymer materials have been extensively studied because of their wide potential applications in biomaterials, separation, sensors, actuators, etc. [ 7 , 8 , 9 ]. A variety of NIPA based polymers with different structures such as linear, branched, cyclic, brush-like, and so on, have been successfully prepared through RAFT polymerization with or without combining other methods [ 10 , 11 , 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Well-Defined Propargyl-Terminated Tetra-Arm Poly(N-isopropylacrylamide)s and Their Click Hydrogels Crosslinked with β-cyclodextrin

et al. 2016

View full text Add to dashboard Cite

As an important class of reversible deactivation radical polymerization (RDRP), reversible addition fragmentation chain transfer (RAFT) polymerization has attracted great attention attributed to its facile and flexible features to prepare well-defined polymers with different complex structures. In addition, the combination of RAFT with click chemistry provides more effective strategies to fabricate advanced functional materials. In this work, a series of temperature responsive tetra-arm telechelic poly(N-isopropylacrylamide)s (PNIPAs) with propargyl end groups were prepared for the first time through RAFT and subsequent aminolysis/Michael addition modification. The temperature sensitivities of their aqueous solutions were researched via turbidity measurement. It was found that the phase transition temperature of obtained PNIPAs increased with their molecular weights ascribed to their distinctions in the hydrophobic/hydrophilic balance. Subsequently, β-cyclodextrin (β-CD) functionalized with azide moieties was used to crosslink the prepared propargyl-terminated tetra-arm PNIPAs through click chemistry, fabricating corresponding hydrogels with thermoresponse. Similar to their precursors, the hydrogels demonstrated the same dependence of volume phase transition temperature (VPTT) on their molecular weights. In addition, the incorporation of β-CD and the residual groups besides crosslinking may provide a platform for imparting additional functions such as inclusion and adsorption as well as further functionalization.

show abstract

“…2,3,5 Poly(N-isopropylacrylamide) (PNIPA), a well-known temperature sensitive polymer whose aqueous solution behaving a lower critical solution temperature (LCST) around 32 C, 6 has been extensively studied in both fundamental and technical aspects, due to their wide potential applications in biomaterials, separation, sensors, actuators, and so on. [7][8][9][10][11] The application of RDRP to NIPA enables the design and synthesis of various well-dened NIPA-based polymers containing special functional groups. Iron oxide/PNIPA core-shell structure was constructed via the "graing-from" NMP of NIPA in the presence of 1,2-diol moiety ended NMP initiator capable of attaching the surface of Fe 2 O 3 nanoparticles.…”

Section: Introductionmentioning

confidence: 99%