“…Although serum levels of ALT and AST can be used to diagnose liver disease, they are less specific markers for this condition, as high AST levels, in particular, are seen following skeletal muscle, brain, heart, and red blood cells damage (Pirmadah et al, 2020; Pratt & Kaplan, 2000). Thus, serum ALT is a better indicator of liver disease due to its higher and more specific expression in hepatic cells (Ruhl & Everhart, 2009; Sampson et al, 1980; Weibrecht, Dayno, Darling, & Bird, 2010). Epidemiological studies have shown an association between these enzymes and the risk of type 2 diabetes (Kunutsor, Apekey, & Walley, 2013), cardiovascular disease (Kunutsor, Apekey, & Khan, 2014), and mortality (Kunutsor, Apekey, Seddoh, & Walley, 2014).…”