An interesting finding in the uterine cervix: Schistosoma hematobium calcified eggs

Toller, Alexia; Scopin, Ana Carolina Carvalho; Apfel, Vanessa; Prigenzi, Karla Calaça Kabbach; Tso, Fernanda Kesselring; Focchi, Gustavo Rubino de Azevedo; Speck, Neila Maria de Góis; Ribalta, Julisa

doi:10.4322/acr.2015.003

Cited by 9 publications

(11 citation statements)

References 10 publications

(14 reference statements)

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“…In this study, schistosomiasis cases were highly noted in cervical tissues (6/501) followed by GIT (2/265), Ureter (2/42) and Liver (2/13). These findings are in support of the data from similar studies which equally detected schistosomiasis infection from cervix and suggestively to be the possible cause of tissue lesions (15,16).…”

Section: Schistosomiasis Remains a Public Health Challenge In Most Ofsupporting

confidence: 90%

Chronic Schistosomiasis, a Clinical and Laboratory Diagnostic Challenge in Malawi

Kamudumuli

Sinyiza

Chisale

et al. 2020

Preprint

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Objective: Schistosomiasis cause significant morbidity and mortality worldwide. This is a retrospective cross-sectional study conducted at Mzuzu Central Hospital (MCH) from northern Malawi aiming at determining prevalence of schistosomiasis infection in cancer suspected patients. The data was collected from hospital files and the duration under review was from July 2013 to June 2018. A total of 790 Histopathological samples were analysed at University of North Carolina (UNC) Histopathology lab. Results were made available to the facility – Mzuzu Central Hospital.Results: The overall prevalence of schistosoma (S. mansoni & haematobium) infection was 1.7% (14/790). About 93% (13/14) of schistosomiasis cases were observed in female patients while 7% (1/14) from male patients. Of the 14 cases from different histopathological pattern (Cervix, Ureter, Liver, Ovary, GIT and Urinary bladder), 43% (6/14) of cases were diagnosed from cervical tissues. Correlation between HIV infection and schistosomiasis infection was not reached as Serostatus for reasonable number of patients was unknown. Schistosomiasis chronic infection is highly prevalent in Malawi. This disease is neglected and underestimated due to lack of clinical skills and capacity in most of the public laboratories to accurately diagnose it as such, most cases are misdiagnosed as cancer.

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Section: Schistosomiasis Remains a Public Health Challenge In Most Ofsupporting

confidence: 90%

Chronic Schistosomiasis, a Clinical and Laboratory Diagnostic Challenge in Malawi

Kamudumuli

Sinyiza

Chisale

et al. 2020

Preprint

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“…Considering that the eggs can find their way to the female genital region and form granulomas in the uterus, fallopian tube and ovaries, if nothing is done soon, there will be high rate of infertility among the populace in the near future [12]. Schistosomtiasis can be cured without progressing to complications if there is an accurate diagnosis and prompt treatment during the initial stages of infection.…”

Section: Discussionmentioning

confidence: 99%

Comparing the Sensitivity of Microscopy to Diagnostic Strip in the Survey for Urinary Schistosomiasis

Musa¹

2018

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Schistosomiasis is one of the Neglected Tropical Diseases (NTDs) recording high morbidity and mortality rate for developing countries in Africa, South America, the Caribbean, the Middle East, and Asia. The sensitivity of microscopy to the use of diagnostic strip in the survey for urinary schistosomiasis among students attending some selected secondary schools was investigated in Chikun Local Government Area of Kaduna State, Nigeria. Four hundred and sixty two (462) urine samples were collected and examined for the eggs of Schistosoma haematobium using sedimentation and microscopy method. Microhaematuria and proteinuria were investigated using combi 11 test strips. This study revealed 11.5% prevalence rate for urinary schistosomiasis among the studied subjects based on direct egg detection method, 22.9% based on micro-haematuria detection and 44.8% based on proteinuria. The sensitivity of Urine dip strip when compared to direct egg detection methods, shows that there is high sensitivity on the use of urine dip strip.

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“…Most of the affected areas suffers inadequate sanitation problems [ 1 ] and depend on rivers and streams as their source of water. The risk of infection is through contact with freshwater infected with the parasite [ 5 , 6 ]. There are five species of Schistosoma parasites that cause the infection in humans; Schistosoma haematobium , Schistosoma mansoni , Schistosoma japonicum , Schistosoma intercalatum and Schistosoma mekongi .…”

Section: Introductionmentioning

confidence: 99%

Detection of cytological abnormalities in urothelial cells from individuals previously exposed or currently infected with Schistosoma haematobium

et al. 2023

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Urinary schistosomiasis has long been associated with bladder cancer, but it is still not clear the mechanisms involved. Schistosoma haematobium causes injury and disruptions in the integrity of the urothelium. The cellular and immunologic responses to the infection lead to the formation of granulomata. The ability to use cellular morphological changes to predict the risk of developing bladder cancer following S. haematobium infection is thus important. This study assessed the cellular changes in the urine associated with schistosomiasis and the potential of routine urine being used as a risk predictor of the development of bladder cancer. Urine samples (160) were screened for the presence of S. haematobium ova. Smears stained with the Papanicolaou method were evaluated using light microscopy to determine the cell populations. A high prevalence (39.9%) of urinary schistosomiasis and haematuria (46.9%) was found among the participants. Polymorphonuclear cells, normal and reactive urothelial cells and lymphocytes were characteristic of S. haematobium infection. Squamous metaplastic cells (SMCs) were found in 48% and 47.1% of participants who have had past or current S. haematobium infection respectively, but were not found in participants who had no exposure to S. haematobium. These squamous metaplastic cells are in transition and are prone to malignant transformation when exposed to a carcinogenic agent. There is still a high burden of schistosomiasis in endemic communities in Ghana. by examining urine, one can find metaplastic cells and? dysplastic cells and thus predict cancer in SH-infested patients. Thus, routine urine cytology as a tool to monitor the risk of bladder cancer development is recommended.

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An interesting finding in the uterine cervix: Schistosoma hematobium calcified eggs

Cited by 9 publications

References 10 publications

Chronic Schistosomiasis, a Clinical and Laboratory Diagnostic Challenge in Malawi

Chronic Schistosomiasis, a Clinical and Laboratory Diagnostic Challenge in Malawi

Comparing the Sensitivity of Microscopy to Diagnostic Strip in the Survey for Urinary Schistosomiasis

Detection of cytological abnormalities in urothelial cells from individuals previously exposed or currently infected with Schistosoma haematobium

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