Proceedings of the 2010 SIAM International Conference on Data Mining 2010
DOI: 10.1137/1.9781611972801.58
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An Integrative Approach to Identifying Biologically Relevant Genes

Abstract: Gene selection aims at detecting biologically relevant genes to assist biologists' research. The cDNA Microarray data used in gene selection is usually "wide". With more than several thousand genes, but only less than a hundred of samples, many biologically irrelevant genes can gain their statistical relevance by sheer randomness. Addressing this problem goes beyond what the cDNA Microarray can offer and necessitates the use of additional information. Recent developments in bioinformatics have made various kno… Show more

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Cited by 13 publications
(4 citation statements)
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“…Figure 1.8 demonstrates how multi-source feature selection works. Recent study shows that the capability of using multiple data and knowledge sources in feature selection may effectively enrich our information and enhance the reliability of relevance estimation [118,225,226].…”
Section: Number Of Data Sourcesmentioning
confidence: 99%
See 1 more Smart Citation
“…Figure 1.8 demonstrates how multi-source feature selection works. Recent study shows that the capability of using multiple data and knowledge sources in feature selection may effectively enrich our information and enhance the reliability of relevance estimation [118,225,226].…”
Section: Number Of Data Sourcesmentioning
confidence: 99%
“…One limitation of MSFS is that it replies on combining sample similarity, which restricts its flexibility in handling small-sample data. To address this limitation we propose in [226] a general approach to systematically integrate different types of knowledge for Knowledge-Oriented multi-source feature selection, named KOFS. Figure 6.6 presents the major steps in the approach.…”
Section: A Framework Based On Rank Aggregationmentioning
confidence: 99%
“…Second, the base feature subsets are integrated together to generate a relatively complete feature subset. Data preprocessing or different feature selection algorithms can be used to generate multiple base feature subsets [16][17] [18][19] [20] . However, some of the previous research methods [15] [19] do not take into account the fitness of different feature selection algorithms to the data set.…”
Section: Introductionmentioning
confidence: 99%
“…Feature selection have been an intense field of study in the recent years, gaining importance in parallel with the dimensionality reduction methods. Feature selection provides an advantage over dimensionality reduction methods because of its ability to distinguish and select the best available features in a data set [6][7][8][9][10]16]. This means that feature selection methods can be applied to both the original feature vectors and to the feature vectors that result from the application of dimensionality reduction methods.…”
mentioning
confidence: 99%