An Integrated Approach for Increasing the Survival of Autologous Fat Grafts in the Treatment of Contour Defects

Har‐Shai, Yaron; Lindenbaum, Ella S.; Gamliel-Lazarovich, Aviva; Beach, Dvora; Hirshowitz, Bernard

doi:10.1097/00006534-199909020-00008

Cited by 80 publications

(28 citation statements)

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“…Fat obtained by lipoaspiration then was available to fill depressions and improve the gluteal shape [13,35,37]. Since the work of Guerrerosantos [16] in 1996 standardized a technique to prolong viability of injected fat in the buttock region, gluteal augmentation by fat grafting has become an increasingly common practice in many centers around the world [20,43].…”

mentioning

confidence: 99%

Magnetic Resonance Imaging Assessment of Gluteal Fat Grafts

et al. 2006

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Backgrounds: One goal of lipoplasty is to create a round and projected buttock contour. Despite multiple papers evaluating lipoinjection, controversies still remain. Methods: This report describes a series of patients who underwent liposuction, gluteal lipoinjection, and evaluation with magnetic resonance imaging (MRI). From January 2003 to January 2004, the patients scheduled for contour surgery by the investigators were evaluated using MRI, photographic records, and gluteal circumference measurement 1 week before surgery, then 2 weeks and 3 months after the procedure. A statistical analysis was performed for 10 patients who received, on the average, a 350-ml injection of fat obtained during liposuction. Results: Gluteus muscle volume increased, reaching a higher level 2 weeks after the injection than the level 3 months afterward (p < 0.001). The gluteal circumference, modified 2 weeks after surgery by about 1 to 3 cm, came back to previous values 3 months after the procedure (p < 0.05), a phenomena interpreted as reabsorption and resolution of the postoperative edema. There is no correlation between the gluteus muscle volume obtained by MRI and the gluteal circumference (p > 0.05). Conclusions:The findings led to the conclusion that enhancement of the gluteal contour after fat injection results from survival of the injected tissue 3 months after the surgery, which was objectively evaluated by MRI as having a calculated reabsorption rate of 24% to 36%.

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confidence: 99%

Magnetic Resonance Imaging Assessment of Gluteal Fat Grafts

et al. 2006

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“…None of these complications were observed in our patient population, probably because the use of fat-PRP mix [51]- [53] and only small amounts of small-diameter fat particles were used, and these were injected into well-vascularized tissue. Bruising was the most common adverse effect (50% of patients) that resolved after approximately 4 days.…”

Section: Discussionmentioning

confidence: 81%

Initial Experience of Face Augmentation Using Fat Graft-Platlet Rich Plasma Mix

Tolba¹,

Nasr²

2015

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Plastic surgeons accustomed to use autologous fat grafs for augmentation of soft tissues in the last two decades. The main drawback of fat grafting is unpredictable graft resorption. Several studies have searched for new ways of increasing the viability of the transplanted tissue to overcome this disadvantage. The most recent and promising approach is to mix the fat graft with Platelet-Rich Plasma (PRP) before transplantation. The purpose of this article is to present the initial experience using the autologous fat injection with platlet rich plasma as a method for fascial augmentation.

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“…These findings were later supported by many experimental, biochemical and histological researches based on biopsies (Carpaneda, Ribeiro, 1993;1994;Niechajev, Sevcuk, 1994;Jauffret, 1998;Moitra et al,1998;Gavrilova et al, 2000;Rieck, Schlaak, 2003) Unfortunately, since then there are not much more means of graft survival or results assessment. After the biopsy of the graft the most informative methods are the magnetic resonance imaging and the 3-D tomodensitometry of the recipient site pre and postoperatively but they are too expensive and not suitable for routine clinical practice (Horl et al, 1991;Liang et al, 1991;Har-Shai, 1999). Echography is not informative.…”

Section: Methods Of Outcomes Assessingmentioning

confidence: 99%

“…0,9% NaCl is experimentaly proved to be not harmful for fat cells viability which makes the method of serum lavage preferable for many authors (Ersek, 1991;Horl et al, 1991;Marques et al, 1994;Fulton, 1998;Har-Shai, 1999;MacRae et al, 2003;Smith at al., 2006;Khater et al, 2008). The method of centrifugation is applied in 3000-3400 rpm for 3 minutes.…”

Section: Graft Processingmentioning

confidence: 99%

“…The optimal conditions are to have anatomically and physiologically undamaged tissue structures with good blood supply. It is proved that fat grafting in zones of fibrosis is done under pressure which leads to structure changes in cells and diminishes the chances of survival (Har-Shai, 1999). For optimal results in these cases a certain repetition of the method is needed and after a few applications a considerable improvement of such a zone quality could be observed .…”

Section: Recipient Sitementioning

confidence: 99%

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