An Independent Analysis of the Copenhagen Sample of the Danish Adoption Study of Schizophrenia

Delusional disorder-somatic type (or body dysmorphic disorder) and schizophrenia: a case report

“…Studies have found that while schizophrenia spectrum disorders were more prevalent in the biologic relatives of the schizophrenic adoptees, the same was not the case for delusional disorder thus pointing out that from a genetic perspective, delusional disorder may not be part of the schizophrenia spectrum. 15,16 These findings were supported by another study that found delusional disorder (compared with schizophrenia, affective illness and psychotic disorders not otherwise specified) as the least prevalent (2.7%) among the probands of patients with schizophrenia. 17 The case describes a case of delusional disordersomatic subtype -preceding schizophrenic illness in a young man.…”

Childhood Precursors of Affective vs. Social Deficits in Adolescents at Risk for Schizophrenia

“…Genetic influences appear to play an important role in the pathogenesis of negative symptoms in schizophrenia (Dworkin and Lenzenweger 1984;Gottesman et al 1987;McGuffin et al 1987;Cannon et al 1990), including anhedonia (Berenbaum et al 1990;Clementz et al 1991;Grove et al 1991). Such influences also appear to play a role in social deficits in schizophrenia (Kendler et al 1982;Dworkin et al 1987Dworkin et al , 1988;;Grove et al 1991), and these genetic influences on affective and social deficits may be at least partially independent (Dworkin et al 1988). In the present data, attentional and neuromotor dysfunction in children at risk for schizophrenia were significantly correlated, but the magnitude of the correlation (r = 0.37) suggests that these two wellresearched indicators of the predisposition to develop schizophrenia are also partially independent.…”

Stressful Life Events and Schizophrenia

“…The definition of illness comprised schizophrenia, schizotypal personality disorder (SPD) and paranoid personality dis order (PPD). SPD and PPD were included in the 'ill' category in view of their purported genetic relationship to schizophrenia [9]. 85% of the relatives were interviewed directly.…”