AnEx VivoModel for Suture-Less Amniotic Membrane Transplantation with a Chemically Defined Bioadhesive

Abstract

CDB provides a satisfactory level of adherence to ex vivo suture-less attachment of equine amniotic membrane transplantation to the porcine cornea.

Degradable Adhesives for Surgery and Tissue Engineering

“…They were shown to have high bonding strength and degradability along with low cytotoxicity. Hyon and co-workers successfully applied these adhesives in lung surgeries, laparoscopic partial nephrectomy, ocular reconstruction, cartilage or bone regeneration, cardiovascular surgery, and as a drug or gene carrier agent. − High aldehyde concentrations are detrimental to tissue and may result in tissue inflammation or tissue necrosis. It is therefore necessary to monitor the aldehyde concentration in the adhesives to avoid cytocompatibility issues.…”