Abstract:Background:
Melasma is a skin pigmentation disorder that remains resistant to available therapies.
The exact cause of melasma is unknown. Histamine is an inflammatory factor. Its involvement in
pigmentation is obscure. The aim of this study is to introduce an herbal antihistamine H2 receptor which is
effective in these disorders.
Methods:
This is a review study by searching the electronic databases and also Persian Medicine books,
from 2000 to 2018 by the keywords such as H2 antagonist, H2 blocker and melasm… Show more
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