An Exceptionally Rare Primary Epithelioid Rhabdomyosarcomas of the Stomach: A Case Report

Abstract

Rhabdomyosarcoma (RMS) is a common soft tissue tumor in adults, but RMS's causes and risk factors are unknown. We present a case of a 62-year-old man with RMS who presented with feelings of fullness after meals and vomiting for the previous five months with anorexia and weight loss for four months. He reported feeling a rolling mass in his belly that moves from left to right. He was initially diagnosed with gastric outlet obstruction due to stomach carcinoma. During the surgical operation, we noted the gross appearance was unlike typical adenocarcinoma or lymphoma of the stomach. Histopathological evaluation of the specimen confirmed a diagnosis of primary epithelial RMS of the stomach. When treating RMS, expertise in immunohistochemistry, molecular biology, genetics, or ultrastructure may be necessary. Information on the appropriate laboratory investigations and management protocol is limited, but an early diagnosis can change the course of treatment and improve patient outcomes.

Primary alveolar rhabdomyosarcoma in the stomach of an adult: A case report

“…Alveolar RMS (ARMS) accounts for 31% of all cases and occurs commonly in individuals aged 10-25 years, mostly in the extremities, followed by the trunk or the perineural region (4). Occurrence in the stomach is extremely rare and an early definitive diagnosis is difficult (5). The tumors are highly malignant and prone to distant lymph node metastasis (6).…”

“…RMS of the stomach is extremely rare, with only four previously published cases (4-7). The reported cases have included epithelioid (4,5), pleomorphic (6) and embryonal (7) RMS of the stomach. To the best of our knowledge, the present study contains the first reported case of primary gastric ARMS.…”