An Essay on the Shaking Palsy, by James Parkinson, M.D., Member of the Royal College of Surgeons

Abstract

A good many years ago my interest in the history of this book was aroused by K. Mendel's statement in his monograph on paralysis agitans to the effect that, notwithstanding his thorough search through the libraries of the German universities, as well as through the Royal Library, and through the larger English libraries, he did not succeed in finding one copy of Parkinson's original description of the disease contained in an octavo booklet, entitled "An Essay on the Shaking Palsy," published in 1817 by Sherwood, Nelly & Jones, London. Charcot in his twentieth "Le\l=c;\on de Mardi," given on June 12, 1888, in his clinic at La Salpetri\l=e'\re, said that it was only after a long search that he was able, through the kindness of the librarian of the University of Manchester, to see and read a copy of this little book. On that morning he advised his students to translate the work into French on account of the excellent description of the disease contained therein. Erich Ebstein, in a bibliographic note contained in the Feb. 15, 1912, number of the Neurologisches Centralblatt, calls attention to the fact that Charcot did not own a copy, as it was never found in his

Anxiety in Parkinson’s disease: identification and management

“…In James Parkinson’s original monograph, An Essay on the Shaking Palsy , brief mention was made of the nonmotor symptoms of anxiety [Ostheimer, 1922]. However, it is now known that clinically significant anxiety symptoms occur in between 20% to greater than 50% of PD patients, a frequency greater than that found in community dwelling age-matched controls [Pontone et al 2011; Richard et al 1996; Dissanayaka et al 2010; Shulman et al 2002].…”

Anxiety in Parkinson’s disease: identification and management

“…In James Parkinson’s original monograph, An Essay on the Shaking Palsy , brief mention was made of the nonmotor symptoms of anxiety [Ostheimer, 1922]. However, it is now known that clinically significant anxiety symptoms occur in between 20% to greater than 50% of PD patients, a frequency greater than that found in community dwelling age-matched controls [Pontone et al 2011; Richard et al 1996; Dissanayaka et al 2010; Shulman et al 2002].…”

Essential Tremor: Diagnosis and Treatment

“…In 1817, James Parkinson differentiated essential tremor from that of other tremors, including parkinsonian tremor ( Table 1). [1][2][3][4][5][6] As the most common movement disorder in the United States, essential tremor occurs across the adult age spectrum, with an overall estimated prevalence similar to that of angina, chronic heart failure, and stroke. 7,8 Surprisingly little is known about the etiology and pathophysiology of essential tremor, which is characterized by pathologic tremor affecting mainly the upper extremities followed by the head and voice.…”

Anxiety in Parkinson’s disease: identification and management

“…In James Parkinson’s original monograph, An Essay on the Shaking Palsy , brief mention was made of the nonmotor symptoms of anxiety [Ostheimer, 1922]. However, it is now known that clinically significant anxiety symptoms occur in between 20% to greater than 50% of PD patients, a frequency greater than that found in community dwelling age-matched controls [Pontone et al 2011; Richard et al 1996; Dissanayaka et al 2010; Shulman et al 2002].…”

Essential Tremor: Diagnosis and Treatment

“…In 1817, James Parkinson differentiated essential tremor from that of other tremors, including parkinsonian tremor ( Table 1). [1][2][3][4][5][6] As the most common movement disorder in the United States, essential tremor occurs across the adult age spectrum, with an overall estimated prevalence similar to that of angina, chronic heart failure, and stroke. 7,8 Surprisingly little is known about the etiology and pathophysiology of essential tremor, which is characterized by pathologic tremor affecting mainly the upper extremities followed by the head and voice.…”

Anxiety in Parkinson’s disease: identification and management

“…In James Parkinson’s original monograph, An Essay on the Shaking Palsy , brief mention was made of the nonmotor symptoms of anxiety [Ostheimer, 1922]. However, it is now known that clinically significant anxiety symptoms occur in between 20% to greater than 50% of PD patients, a frequency greater than that found in community dwelling age-matched controls [Pontone et al 2011; Richard et al 1996; Dissanayaka et al 2010; Shulman et al 2002].…”

Essential Tremor: Diagnosis and Treatment

“…In 1817, James Parkinson differentiated essential tremor from that of other tremors, including parkinsonian tremor ( Table 1). [1][2][3][4][5][6] As the most common movement disorder in the United States, essential tremor occurs across the adult age spectrum, with an overall estimated prevalence similar to that of angina, chronic heart failure, and stroke. 7,8 Surprisingly little is known about the etiology and pathophysiology of essential tremor, which is characterized by pathologic tremor affecting mainly the upper extremities followed by the head and voice.…”