An epidemiological evaluation of the prevalence of malnutrition in Spanish patients with locally advanced or metastatic cancer

Segura, Ángel; Pardo, J.; Jara, Carlos; Zugazabeitia, Luis; Carulla, Joan; Peñas, R. de las; García-Cabrera, Encarna; Azuara, María Luz; Casado, J Castejón; Gómez-Candela, Carmen

doi:10.1016/j.clnu.2005.05.001

Cited by 187 publications

(152 citation statements)

References 27 publications

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“…In this study, 41.3% of patients reported some type of side effect at the end of the studied period, with dry mouth being the most common, followed by lack of appetite, early satiety and nausea. A Spanish study of cancer patients showed that the most common complaints were loss of appetite (42.2%) and early satiety (21.5%) 21 . Since the PG-SGA enabled early detection of side effects, the institution of appropriate nutritional and pharmacological measures prevented further deterioration of nutritional status.…”

Section: Discussionmentioning

confidence: 99%

Can nutritional status influence the quality of life of cancer patients?

et al. 2010

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Rev. Nutr., Campinas, 23 (5) A B S T R A C T ObjectiveThis study aimed to evaluate the influence of nutritional status on the quality of life of a cohort of cancer patients submitted to chemotherapy. MethodsPatients receiving chemotherapy for the first time in a University Hospital in Pelotas (RS), Brazil, were evaluated prospectively. Their nutritional risk was determined by the Patient-Generated Subjective Global Assessment scores and their quality of life by the World Health Organization's quality of life questionnaire, administered at the beginning and end of the study. ResultsOne hundred and forty-three patients were studied, 76.2% being females. The prevalence of malnutrition at baseline was 14.0%. The present study found that malnourished patients had a poor quality of life. The nutritional risk of 41.6% of the patients increased after chemotherapy. A significant association was found between the presence of symptoms and increased nutritional risk (p<0.001). Additionally, there was a significant negative correlation between physical domain and nutritional risk scores, showing that quality of life increases as nutritional risk decreases.

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Section: Discussionmentioning

confidence: 99%

Can nutritional status influence the quality of life of cancer patients?

et al. 2010

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“…1). These figures for the prevalence of malnutrition with a malignant condition are relatively moderate when compared to other gastroenteropancreatic tumour entities such as oesophageal cancer (55-65%) [10], gastric cancer (30-45%) [10,13,14], pancreatic cancer (up to 70%) [15], colorectal cancer (40-60%) [14,16,17] or non-gastroenteropancreatic entities such as lung cancer (20-50%) [11,12], breast cancer (20-30%) [16] or ovarian cancer (20-50%) [18,19,20]. This may be attributable to the fact that in the majority of cases NEN present as rather slowly growing neoplasms, presumably with a rather moderate ‘cachexia-inducing' potential, which is also reflected in the rather good long-term prognosis, with 5- and 10-YSR of 40-60% in stage IV patients and even better figures in early-stage patients [28,32,36,37,62].…”

Section: Discussionmentioning

confidence: 99%

“…This is particularly true for patients with solid neoplasms [9,10] such as lung [11,12], gastric [10,13,14], pancreatic [14,15], colorectal [14,16,17], ovarian [18,19,20] or breast cancers [16]. Consequences resulting from malnutrition include increased complication rates after oncological surgery, an increased duration of hospitalization mostly due to a higher number of infectious complications, increased side effects of cytotoxic treatment, a decreased response to treatment, a poorer quality of life and ultimately a worse prognosis in malnourished cancer patients [7,9,12,14,21,22,23,24,25].…”

Section: Introductionmentioning

confidence: 99%

Malnutrition Predicts Clinical Outcome in Patients with Neuroendocrine Neoplasia

et al. 2015

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Malnutrition is a common problem in oncological diseases, influencing treatment outcomes, treatment complications, quality of life and survival. The potential role of malnutrition has not yet been studied systematically in neuroendocrine neoplasms (NEN), which, due to their growing prevalence and additional therapeutic options, provide an increasing clinical challenge to diagnosis and management. The aim of this cross-sectional observational study, which included a long-term follow-up, was therefore to define the prevalence of malnutrition in 203 patients with NEN using various methodological approaches, and to analyse the short- and long-term outcome of malnourished patients. A detailed subgroup analysis was also performed to define risk factors for poorer outcome. When applying malnutrition screening scores, 21-25% of the NEN patients were at risk of or demonstrated manifest malnutrition. This was confirmed by anthropometric measurements, by determination of serum surrogate parameters such as albumin as well as by bioelectrical impedance analysis (BIA), particularly phase angle α. The length of hospital stay was significantly longer in malnourished NEN patients, while long-term overall survival was highly significantly reduced. Patients with high-grade (G3) neuroendocrine carcinomas, progressive disease and undergoing chemotherapy were at particular risk of malnutrition associated with a poorer outcome. Multivariate analysis confirmed the important and highly significant role of malnutrition as an independent prognostic factor for NEN besides proliferative capacity (G3 NEC). Malnutrition is therefore an underrecognized problem in NEN patients which should systematically be diagnosed by widely available standard methods such as Nutritional Risk Screening (NRS), serum albumin assessment and BIA, and treated to improve both short- and long-term outcomes.

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“…Progressive weight loss and malnutrition are commonly found in cancer patients (not only when in hospital), and especially in those with hnc, but also in those with lung and gastrointestinal cancers 3,4 . Weight loss during treatment for hnc is a major concern.…”

Section: Introductionmentioning

confidence: 99%