Sarah Fink, Kira Turnbull, Arshad Desai, Christopher S. Campbell
Abstract:The chromosomal passenger complex (CPC), which includes the Aurora B kinase and the scaffold Sli15/INCENP, promotes chromosome biorientation. Fink et al. engineer a minimal CPC construct made of Aurora B and Sli15/INCENP and determine how specific protein domains contribute to chromosome biorientation.
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