An Eczematous Reaction Associated with Molluscum Contagiosum

Molluscum contagiosum: a case series

“…3 In at least 10% of cases, particularly in atopic subjects, a patchy eczema, often very irritable, develops around the lesions. 4 Complications include secondary bacterial infection and involvement of mucosal surfaces, especially the conjunctiva resulting in follicular or papillary conjunctivitis. 5 Rarely, superficial punctate keratitis may develop as well.…”

Molluscum Contagiosum‐Induced Comedo and Secondary Abscess Formation

“…This fact has been attributed to the finding of a unique, well-defined sac enclosing the virion colony of each infected keratinocyte, which favors replication of the virions by providing a site that is both anatomically and immunologically privileged (5). Inflammatory changes may be noted in regressing lesions, however, as a lymphocytemediated rejection (6), The localized, eczematous reaction occasionally noted around molluscum papules (molluscum dermatitis) has been interpreted as a delayed hypersensitivity reaction to the molluscum virus antigen (7,8), Furthermore, widespread eruptions of molluscum contagiosum, without signs of regression, described in severely immunocompromised hosts (9,10) point to the importance of T lymphocyte-mediated immune reactions for resistance to and clearance of this infection.…”