An Audit of Gastroduodenal Crohn Disease: Clinicopathologic Features and Management

Abstract

Gastroduodenal Crohn disease is a complex and difficult problem that is associated with serious complications and need for reoperation.

Isolated Duodenal Crohn's Disease: A Case Report and a Review of the Surgical Management

“…Patients with DCD usually present with Crohn's disease affecting other areas of the gastrointestinal tract; however, isolated DCD is a very rare clinical entity [1, 4]. Initially, patients with DCD are managed with a combination of antiacid and immunosuppressive therapy.…”

“…Since then, DCD still remains a complex clinical entity with a controversial management of the disease. The most common site of duodenal Crohn's disease is the duodenal bulb, and obstruction is the most frequent presentation [1, 4]. Medical management with antiinflammatory and antiacid medications is effective in patients without obstruction.…”

Crohn′s disease: A surgeon′s perspective

“…[12] Oral CD presents with aphthous ulcers over the hard palate. Esophageal CD is very rare and is believed to be more common in children than adults.…”

Duodenal-Pleural Fistula in Crohnʼs Disease

“…As medical therapy evolved, some patients, certainly not all, could be managed non-operatively with corticosteroids, acid suppression, immunosuppressives and/or antibiotics 1, 6 . More recently, infliximab has been used successfully to successfully treat obstructing duodenal Crohn’s disease 7 .…”

“…Simple fistula closure was performed in one case and duodeno-jejunostomy in the other. Both were eventually successful, but complicated by post-operative abscess 1, 8 . Medical therapy for a primary duodenal fistula has not been previously described.…”