An alternative to treat palmar hyperhidrosis: use of oxybutynin

Abstract

The use of oxybutynin is an alternative as the first step in the treatment of palmar hyperhidrosis, given that it presents good results and improves QOL.

Compensatory Hyperhidrosis: Results of Pharmacologic Treatment With Oxybutynin

“…Recently, this treatment was reported [10,11] as an initial alternative treatment for primary hyperhidrosisfor plantar [12], axillary [13], palmar, [14,15] and facial [16] sweating-and it has been evaluated in a randomized placebo-controlled trial [17]. However, there are no published articles describing its use in the treatment of CH.…”

A randomized placebo-controlled trial of oxybutynin for the initial treatment of palmar and axillary hyperhidrosis

“…The use of oxybutynin for treating primary hyperhidrosis has only been described in three case reports, [10][11][12] one series of 14 patients with compensatory hyperhidrosis after VATS, 13 one publication about facial hyperhidrosis, 14 one publication of AH, 15 and one publication of PH. 16 To our knowledge, no studies have compared the use of oxybutynin vs placebo in the treatment of PH or AH.…”

Oxybutynin as an alternative treatment for hyperhidrosis

“…35-50 Following a standard protocol, they used a dose of 2.5mg per day in the first week, 5mg a day divided in two doses from day 8 up to day 42, and 10mg daily in two doses from day 43 up to day 84 (12 weeks). The method of assessing the response to treatment was always performed by questionnaires completed by patients.…”