An alternative approach to obesity treatment: intermittent fasting

Özyildirim, Caner; Uçar, Aslı

doi:10.23736/s2724-6507.21.03596-x

Cited by 5 publications

(1 citation statement)

References 92 publications

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“…Initially, it was developed as therapeutic treatment for pharmacoresistant epilepsy; subsequently, due to its effect in lowering glucose plasma levels, it has been proposed to take advantage of altered metabolism in cancer [ 25 ]. Moreover, it has been reported that the low carbohydrate composition (<50 g) is associated with a decreased level of obesity [ 56 , 57 , 58 ], body weight, and inflammation [ 59 ]. These assumptions have grown the clinicians’ interest in the effect of KD application on cancer patients, and, nowadays, emerging results have been reported, as subsequently described.…”

Section: Management Of Tumors Though Nutritional Approachesmentioning

confidence: 99%

Neuroendocrine Tumors: A Comprehensive Review on Nutritional Approaches

Muscogiuri

Barrea

Cantone

et al. 2022

Cancers

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Neuroendocrine neoplasms are a heterogeneous group of neoplasms with increasing incidence, high prevalence, and survival worldwide. About 90% of cases are well differentiated forms, the so-called neuroendocrine tumors (NETs), with slow proliferation rates and prolonged survival but frequent development of liver metastases and endocrine syndromes. Both the tumor itself and systemic therapy may have an impact on patient nutrition. Malnutrition has a negative impact on outcome in patients with NETs, as well as obesity. In addition, obesity and metabolic syndrome have been shown to be risk factors for both the development and prognosis of NET. Therefore, dietary assessment based on body composition and lifestyle modifications should be an integral part of the treatment of NET patients. Nutrition plans, properly formulated by a dietician, are an integral part of the multidisciplinary treatment team for patients with NETs because they allow an improvement in quality of life, providing a tailored approach based on nutritional needs and nutritional manageable signs and/or symptoms related to pharmacological treatment. The aim of this review is to condense the latest evidence on the role of the most used dietary models, the Mediterranean diet, the ketogenic diet, and intermittent fasting, in the context of NETs, while considering the clinical and molecular mechanisms by which these dietary models act.

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