An accurate estimation of bone density improves the accuracy of subject-specific finite element models

Schileo, Enrico; Dall’Ara, Enrico; Taddei, Fulvia; Malandrino, Andrea; Schotkamp, Tom; Baleani, Massimiliano; Viceconti, Marco

doi:10.1016/j.jbiomech.2008.05.017

Cited by 289 publications

(218 citation statements)

References 38 publications

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“…6 The assignment of inhomogeneous material properties to the FE mesh relied on algorithms patented by Simpleware. 7 The Omega3 Compression Hip Screw, a typical sliding hip screw currently manufactured by Stryker Osteosynthesis (Schoenkirchen, Germany), was used to stabilize our trochanteric fracture model.…”

Section: Methodsmentioning

confidence: 99%

The importance of lag screw position for the stabilization of trochanteric fractures with a sliding hip screw: A subject‐specific finite element study

Goffin

Pankaj

Simpson

2012

Journal Orthopaedic Research

105

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Using finite element analysis, we compared the biomechanical performance of a CT scan-based three-part trochanteric fracture model (31-A2 in the AO classification) stabilized with a sliding hip screw for nine different positions of the lag screw (3 Â 3 arrangement, from anterior to posterior and from inferior to superior). Our results showed that the volume of bone susceptible to yielding in the head and neck region is the lowest for inferior positions and increases as the lag screw is moved superiorly. Overall, for this specific subject, the models less likely to lead to cut-out are the ones corresponding to inferior middle and inferior posterior positions of the lag screw. In our study, the tip-apex distance (TAD) was anti-correlated with the risk of cut-out, as quantified by the volume of bone susceptible to yielding, which suggests that a TAD >25 mm cannot be considered to be an accurate predictor of lag screw cut-out. Further clinical studies investigating lag screw cut-out should attempt to find more reliable predictors of cut-out that should better reflect the biomechanics and subject-specificity of the femoral head. ß

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Section: Methodsmentioning

confidence: 99%

The importance of lag screw position for the stabilization of trochanteric fractures with a sliding hip screw: A subject‐specific finite element study

Goffin

Pankaj

Simpson

2012

Journal Orthopaedic Research

105

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“…The derivation of Dapp is not contested because it is simply the wet bone mass of a sample over the Cartesian geometric volume occupied by the same bone sample. Different methods for material density, however, have caused some debate (Schileo et al, 2008;Zioupos et al, 2008). The most conventional technique employed for this assessment relies on the Archimedes principle (usually via water displacement).…”

mentioning

confidence: 99%

Bone Apparent and Material Densities Examined by Cone Beam Computed Tomography and the Archimedes Technique: Comparison of the Two Methods and Their Results

et al. 2018

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An understanding of bone apparent and material densities and how they vary within bone at the organ level is of great interest in the understanding of degenerative bone conditions and for biomedical engineering applications. The densities of bone tissue have been shown to appreciably influence the mechanical competency of bone tissue. In order to assess the density of bone in the body, it is important to ensure that the parameters being measured in vivo are truly representative of the real values that have been measured in vitro. To assess the densities of bone across the entire spectrum of available porosities, 112 samples from an elephant femur were assessed using the Archimedes method (water displacement) and by micro-computed tomography (μ-CT). Comparisons were drawn between the two methods to determine if the densities calculated by μ-CT were representative of physically measured densities. The results showed that the apparent densities measured over the entire spectrum were very similar but varied in the intermediate regions of bone tissue, probably due to an increased presence of osteoid, increased remodeling, or experimental error as these type of bone is known for the presence of regions of closed cell geometry in the cancellous architecture. It could be argued that the measurements taken by μ-CT are more reliable of bone density values for the mineralized regions of bone as the threshold is defined with respect to the absorption of X-rays by the mineral. In contrast, the Archimedes method thresholds everything with a density value above that of the surrounding medium, 1 (g cm ) for water, and hence it is more sensitive to the presence of osteoid, soft collagenous matrix, and epithelial cell layers. Further research is required to optimize the parameters of scanning methods for the structural properties of different bone tissue porosities, which hopefully in turn will be able to provide a basis for the development of predictive remodeling models.

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“…Furthermore, the bone's surface was approximated by piecewise flat tessellation or piecewise parabolic tessellation, introducing un-smoothness of the surface and inaccuracies in the surface strains. Among the vast literature addressing h-FE simulations of the femur, the recent ones that present results which are closest to experimental observations are [8,9].…”

Section: Introductionmentioning

confidence: 95%

“…It is important to realize that the use of the Total-Lagrange formulation does not require to update the FE mesh, and hence the Jacobian [J ] is determined once, relative to the material (undeformed) configuration. The updates from one iteration to the next are performed by updating the integrand terms due to the update of the displacements (8).…”

Section: P-fem Implementationmentioning

confidence: 99%

p-FEMs in biomechanics: Bones and arteries

Yosibash

2012

Computer Methods in Applied Mechanics and Engineering

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An accurate estimation of bone density improves the accuracy of subject-specific finite element models

Cited by 289 publications

References 38 publications

The importance of lag screw position for the stabilization of trochanteric fractures with a sliding hip screw: A subject‐specific finite element study

The importance of lag screw position for the stabilization of trochanteric fractures with a sliding hip screw: A subject‐specific finite element study

Bone Apparent and Material Densities Examined by Cone Beam Computed Tomography and the Archimedes Technique: Comparison of the Two Methods and Their Results

p-FEMs in biomechanics: Bones and arteries

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