Volkan Adsay, Nobuyuki Ohike, Takuma Tajiri, Grace E. Kim, Alyssa Krasinskas, Serdar Balci, Pelin Bagci, Olca Basturk, Sudeshna Bandyopadhyay, Kee-Taek Jang, David A. Kooby, Shishir K. Maithel, Juan Sarmiento, Charles A. Staley et al.
Abstract:Ampullary (AMP) carcinomas comprise a heterogeneous group of cancers lacking adequate subcategorization. In the present study, 249 strictly defined primary AMP carcinomas (ACs) identified in 1469 malignant pancreatoduodenectomy specimens were analyzed for defining features. Gross and microscopic findings were used to determine tumor epicenter and extent of preinvasive component. ACs were classified into 4 distinct subtypes based on location: (1) Intra-AMP (25%): Invasive carcinomas arising in intra-ampullary p…
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