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Cited by 5 publications
(2 citation statements)
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“…The fall in urine pH observed in these studies, with a lowest value of 5.15 and average of 5.92, is comparable with the expected degree of urinary acidification in the rat in vivo, where urine pH ranges between 5.3 and 6.1 in acute acidosis (Benyajati & Goldstein, 1975;Bourke, Asatoor & Milne, 1972;Goldstein, 1970;Hems & Brosnan, 1971; Leonard & Orloff, 1955;Roscoe, Goldstein, Halperin, Schoeder & Stinebaugh, 1977;Seldin, Teng & Rector, 1957). This contrasts with the more marked acidification which is achieved by the dog or human kidney in vivo.…”
Section: Discussionsupporting
confidence: 68%
“…In the present study, there was initially a small but significant rise in the excretion of acid (both as ammonia and titratable acid) during the first day or two of acidosis; thereafter, despite continued, severe, systemic acidosis, urinary acid excretion returned virtually to control values. By contrast, the administration of an acid buffer, such as sodium acid phosphate, promptly increases the excretion of titratable acid as long as the acid load is given, even though the amounts of acid cause only a slight lowering of the concentration of serum bicarbonate (24).…”
Section: Discussionmentioning
confidence: 99%