2005
DOI: 10.1007/s00280-004-0956-1 View full text |Buy / Rent full text
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Abstract: Pretreatment with AGBE and its major constituent, Re, attenuated cisplatin-induced pica, and demonstrated potential for the treatment of chemotherapy-induced nausea and vomiting. Significant recovery of food intake further strengthens the conclusion that AGBE may exert an antinausea/antiemetic effect.

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“…We previously investigated the effects of several herbal extracts on reducing chemotherapeutic side-effects and found that American ginseng can attenuate cisplatininduced nausea and vomiting in a rat model, while not affecting its anti-cancer properties in human cancer cells (Mehendale et al, 2005;Aung et al, 2007). In addition, the extract from American ginseng enhanced the anti-proliferation effect of cisplatin on human breast cancer cells, suggesting that it possesses its own anti-cancer activity (Aung et al, 2007).…”
Section: American Ginsengmentioning
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rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…We previously investigated the effects of several herbal extracts on reducing chemotherapeutic side-effects and found that American ginseng can attenuate cisplatininduced nausea and vomiting in a rat model, while not affecting its anti-cancer properties in human cancer cells (Mehendale et al, 2005;Aung et al, 2007). In addition, the extract from American ginseng enhanced the anti-proliferation effect of cisplatin on human breast cancer cells, suggesting that it possesses its own anti-cancer activity (Aung et al, 2007).…”
Section: American Ginsengmentioning
“…37) In this study, in vitro and in vivo data suggested that S-AGE possessed a direct colorectal cancer inhibitory effect in addition to the reduction of chemotherapy induced side effects. The synergistic activities of S-AGE with chemotherapeutic agents will be explored in the future studies.…”
Section: Discussionmentioning
“…However, the antiproliferative effects of AGE on the other two cell lines were less than on HCT-116. At 1.0 mg/ml, the AGE inhibited cell growth by 37 Fig. 2A).…”
Section: High Performance Liquid Chromatographic Analyses Of Age and mentioning
“…Recent studies have reported that the ginseng berry also exhibits anti-cancer activity in in vitro [2,[73][74][75][76][77] side effects [80,81]; these effects result from the promotion of dendrite cell maturation. Interestingly, the ginseng berry induced a higher degree of co-stimulatory molecule up regulation than the root extract at the same concentrations [82].…”
Section: Anti-cancer Activitymentioning