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Cited by 215 publications
(159 citation statements)
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References 109 publications
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“…A considerable number of elderly patients with newly diagnosed early-stage NSCLC have reduced pulmonary reserve (24). In these patients, limited resections are usually indicated owing to the lower risk of postoperative respiratory failure, perioperative mortality, and long-term disability (24)(25)(26).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…A considerable number of elderly patients with newly diagnosed early-stage NSCLC have reduced pulmonary reserve (24). In these patients, limited resections are usually indicated owing to the lower risk of postoperative respiratory failure, perioperative mortality, and long-term disability (24)(25)(26).…”
Section: Discussionmentioning
confidence: 99%
“…In these patients, limited resections are usually indicated owing to the lower risk of postoperative respiratory failure, perioperative mortality, and long-term disability (24)(25)(26). Given the higher risk of recurrence associated with limited resection, we investigated whether PORT or adjuvant chemotherapy, individually or in combination, are associated with improved patient outcomes.…”
Section: Discussionmentioning
confidence: 99%
“…This particular experiment recognised lobectomy as the benchmark surgical technique for early stage NSCLC since the recurrence rate was significantly lower, although only a minor increase in overall survival was reported (10). However, over the last decade, predominantly single institution retrospective series have demonstrated equivalent regional recurrence and survival rates for sublobar resections compared with lobectomy for small node-negative tumours (11). Specifically, anatomic segmentectomy may result in better recurrence-free survival compared with wedge resection and have almost similar rates of recurrence and survival following lobectomy (11,(12)(13).…”
Section: Advantages Of Surgerymentioning
confidence: 99%
“…At present, lobectomy with systematic mediastinal lymph node dissection remains the gold standard for early-stage lung cancer. This statement has been re-emphasised recently by a panel of experts from the American College of Chest Physicians and the STS [16]. Lobectomy versus segmentectomy In a landmark paper, Ginsberg and the Lung Cancer Study Group showed that lobectomy should be preferred to wedge resection or segmentectomy whenever possible, as it resulted in a much lower local recurrence rate and better cancer-free survival [58].…”
Section: Surgery For Early Stage Lung Cancer (Stage I and Ii)mentioning
confidence: 99%
“…More recently, robotic approaches have been proposed in order to reduce the operative trauma, facilitate the surgical procedure and reduce the length of hospital stay [15]. All these techniques have yet to be validated and are currently being compared to conventional surgery in prospective randomised trials [5,16].…”
Section: Introductionmentioning
confidence: 99%