volume 297, issue 2, PH680-H688 2009
DOI: 10.1152/ajpheart.00109.2009
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Abstract: 2) channels are the primary Ca 2ϩ entry pathway in smooth muscle cells of resistance-size (myogenic) arteries, but their molecular identity remains unclear. Here we identified and quantified Ca V1.2 ␣1-subunit splice variation in myocytes of rat resistance-size (100 -200 m diameter) cerebral arteries. Full-length clones containing either exon 1b or the recently identified exon 1c exhibited additional primary splice variation at exons 9*, 21/22, 31/32, and Ϯ 33. Real-time PCR confirmed the findings from full-l…

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