volume 27, issue 3, P603-613 2011
DOI: 10.3233/jad-2011-110446
View full text
|
Sign up to set email alerts
|
Share

Abstract: The microtubule associated protein tau plays a crucial role in Alzheimer's disease and in many neurodegenerative disorders collectively known as tauopathies. Recently, tau pathology has been also documented in prion diseases although the possible molecular events linking these two proteins are still unknown. We have investigated the fate of normal cellular prion protein (PrP(C)) in primary cortical neurons overexpressing tau protein. We found that overexpression of tau reduces PrP(C) expression at the cell sur…

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

1
8
0

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals