Journal of Cell Biology volume 217, issue 4, P1319-1334 2018 DOI: 10.1083/jcb.201708179 View full text
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Yang Yue, T. Lynne Blasius, Stephanie Zhang, Shashank Jariwala, Benjamin Walker, Barry J. Grant, Jared C. Cochran, Kristen J. Verhey

Abstract: Despite their shared ability to regulate microtubule polymerization dynamics, kinesin-4 motors display dramatically different motility properties ranging from fast processive motility to no movement. Yue et al. demonstrate that for KIF7 and KIF27, altered chemomechanical coupling results in immotile behavior and slow processive movement, respectively.