volume 32, issue 3, P529-534 2002
DOI: 10.1590/s0103-84782002000300027
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Abstract: RESUMO Em geral, todos os efeitos dos antiinflamatórios estão relacionados com a inibição da ciclo-oxigenase (COX) do SUMMARY In general, all effects of the antiinflammatory drugs are related to the inhibition of the arachidonic acid and inhibition of prostaglandins and tromboxans production. Two types of ciclooxygenasis (COX) exist, which are COX-1 and COX-2. COX-1 is a constitutional enzyme expressed in many sites, including platelets, and is involved in tecidual homeostasis. On the other hand, COX-2 is ind…

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