Alopecia Mucinosa

Pinkus, Hermann

doi:10.1001/archderm.1957.01550220027005

Cited by 174 publications

(18 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The authors called it basaloid follicular hyperplasia. It had been observed previously in follicular mucinosis [8]. In one of our cases similar findings were present, but were considered atrophic telogen structures undergoing involution, possibly secondary to the lymphocytic epidermotropism and the focal mucinosis.…”

Section: Discussionsupporting

confidence: 89%

Alopecia Universalis Associated with Cutaneous T Cell Lymphoma

et al. 2014

View full text Add to dashboard Cite

Background: Alopecia areata-like hair loss may occur in the context of cutaneous T cell lymphoma (CTCL) and can very rarely evolve to alopecia universalis-like presentation. The dermoscopic findings of CTCL-related alopecia have not been described. Methods: Two patients with alopecia areata universalis-like hair loss occurring in the context of preexisting, pathology-proven CTCL are presented. Results: Clinical examination showed subtotal scalp alopecia with sparse fine hair or total scalp alopecia with loss of eyebrows, eyelashes and body hair. On dermoscopy there was follicular or diffuse scaling, reduced number of follicular openings with broken hairs, short hairs or keratotic filiform spicules. Pathology confirmed the diagnosis of CTCL-related alopecia. One patient had almost complete hair regrowth after treatment. Conclusion: CTCL-related alopecia universalis is a rare non-scarring form of hair loss which simulates alopecia areata universalis. We provide clues to distinguish both based on clinical, dermoscopic and pathologic findings.

show abstract

Section: Discussionsupporting

confidence: 89%

Alopecia Universalis Associated with Cutaneous T Cell Lymphoma

et al. 2014

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 83%

“…This is in contrast to cases of Alopecia mucinosa reported in literature including the first report of six cases by Pinkus[3] in which multiple erythematous papules and plaques occur over the head and neck region.Treatment of alopecia mucinosa The lesions of Alopecia mucinosa tend to persist for months or years and may show spontaneous clearing, however, in general the therapy for alopecia mucinosa remains nonspecific as no single agent has been shown to consistently improve this condition. [4] In contrast all our cases showed a remarkable consistency in rapid and complete response to antileprosy treatment.…”

Section: Discussionmentioning

confidence: 84%

See 1 more Smart Citation

Alopecia mucinosa responding to antileprosy treatment: Are we missing something?

Joshi

Gopalani²

2013

Indian J Dermatol

View full text Add to dashboard Cite

Three cases with single lesion of Alopecia mucinosa (follicular mucinosis) were treated with antileprosy treatment and showed rapid and complete resolution of the lesions with no recurrence on extended follow-up. Two children, a boy aged 14 years and a girl aged 12 years presented themselves, each, with a single hypopigmented, hypoesthetic patch on the face. Clinically leprosy was suspected, however, skin biopsy from both patients revealed follicular mucinosis as the only pathological finding, without any granulomas. Based on clinical suspicion both were started on multi drug therapy (MDT) for leprosy with complete resolution of the lesions. The third case, male, aged 22 years presented with a single erythematous, hypoesthetic plaque on the forehead. This lesion had been diagnosed as follicular mucinosis with folliculo-tropic mycosis fungoides, in the USA. He too responded completely within 3 months with rifampicin, ofloxacin, minocycline (ROM) treatment, which was given once monthly for a total of 6 months and remains free of disease since the past 1 year. Follicular mucinosis as the only pathology may be seen in facial lesions of clinically suspected leprosy in children and young adults. Based on histological findings these cannot be diagnosed as leprosy and will be considered as Alopecia mucinosa. These lesions, however, are always single and show rapid and complete response to antileprosy treatment. The authors suggest that in regions endemic for leprosy, such as India, single lesion Alopecia mucinosa on the face in children and young adults should be given antileprosy treatment.

show abstract

“…It has also been used to investigate the SC physiology as well as the kinetics and penetration depth of topical drugs [14][15][16][17]. During the tape stripping process, the skin is usually applied with appropriate adhesive tapes, and the SC is sequentially removed by a serial number of stripping procedures [18]. This is considered as a minimally invasive technique and is the basis of the FDA's socalled dermatopharmacokinetic (DPK) approach to the assessment of topical bioavailability and bioequivanlence [19].…”

Section: Introductionmentioning

confidence: 99%

In vivo blood flow imaging of inflammatory human skin induced by tape stripping using optical microangiography

Wang

Baran

Wang

2014

Journal of Biophotonics

View full text Add to dashboard Cite

Vasculature response is a hallmark for most inflammatory skin disorders. Tape stripping on human skin causes a minor inflammation which leads to changes in microvasculature. In this study, optical microangiography (OMAG), noninvasive volumetric microvasculature in vivo imaging method, has been used to track the vascular responses after tape stripping. Vessel density has been quantified and used to correlate with the degree of skin irritation. The proved capability of OMAG technique in visualizing the microvasculature network under inflamed skin condition can play an important role in clinical trials of treatment and diagnosis of inflammatory skin disor-ders. UHS-OMAG images of the skin at (a) before tape stripping, (b) 1 min, (c) 6 min, and (d) 15 min after stripping. Scale bar: 0.3 mm.

show abstract

Alopecia Mucinosa

Cited by 174 publications

References 0 publications

Alopecia Universalis Associated with Cutaneous T Cell Lymphoma

Alopecia Universalis Associated with Cutaneous T Cell Lymphoma

Alopecia mucinosa responding to antileprosy treatment: Are we missing something?

In vivo blood flow imaging of inflammatory human skin induced by tape stripping using optical microangiography

Contact Info

Product

Resources

About