Alopecia areata and vitiligo associated with Down's syndrome

Brown, A. C.

doi:10.1001/archderm.113.9.1296b

Cited by 11 publications

(2 citation statements)

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“…Scattered reports exist on vitiligo in association with various disorders, such as derrnatitis herpetifonnis, acromegaly, parapsoriasis, erythema dyschromicum perstans, porphyria cutanea tarda, and lichen sclerosis et atrophicus (12)(13)(14)(15). Vitiligo also has been observed in rare syndromes such as Vogt-Koyanagi-Harada syndrome, Castleman's disease, Evan's syndrome, and Down's syndrome (16)(17)(18). However, we could not find any report of coexistent of vitiligo and ND in the English literature.…”

Section: Discussionmentioning

confidence: 54%

Vitiligo Coexistent with Nevus Depigmentosus

Kang

Hann

1996

The Journal of Dermatology

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A 45-year-old Korean man had two distinct types of hypopigmented lesions on the forehead and back: vitiligo and nevus depigmentosus (ND). The hypopigmented macules on the forehead were incidentally discovered 15 days previously and responded well to steroid therapy. The hypopigmented macule on the back had been present since birth, was stable in size, and showed no response to steroid therapy. There were no remarkable differences between the two lesions in routine histopathology or Fontana-Masson staining. However, the lesion on the back was shown to contain melanocytes in electron microscopy (EM).

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Section: Discussionmentioning

confidence: 54%

Vitiligo Coexistent with Nevus Depigmentosus

Kang

Hann

1996

The Journal of Dermatology

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“…Alopecia areata is a chronic inflammatory disease characterized by patchy hair loss with T-cell infiltration of hair follicles. It occurs in approximately 0.1 % of the general population [26], but in approximately 9 % of patients with Down syndrome [27]. Genetic background.…”

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confidence: 99%

Differential diagnosis of hair loss in children

Mandt

Vogt

Blume‐Peytavi

2004

J Deutsche Derma Gesell

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Hair loss in childhood covers a broad differential diagnosis and often presents the involved dermatologist and pediatrician with a diagnostic and therapeutic challenge. Correct classification of the hair disease, especially in the case of underlying genetic syndromes, metabolic defects or endocrine disorders, is often an important prerequisite for continued normal physical and mental development of the young patients. Dealing with hair loss in childhood, one should differentiate between congenital and acquired diseases. The clinical manifestation profile, the age of the patient when the initial manifestation occurred, and the presence of associated symptoms are important for the classification of the hair disease. In the present paper, a classification of hair loss in childhood based on clinical appearance, age of onset and associated symptoms is proposed as a guide for the evaluation of hair loss and alopecia in childhood.

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Hair Loss in Children

Bartels

Blume‐Peytavi

Hair Growth and Disorders

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Alopecia areata and vitiligo associated with Down's syndrome

Cited by 11 publications

References 0 publications

Vitiligo Coexistent with Nevus Depigmentosus

Vitiligo Coexistent with Nevus Depigmentosus

Differential diagnosis of hair loss in children

Hair Loss in Children

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