Allergic Rhinitis and Chronic Spontaneous Urticaria

Dziewa, Iwona; Rosenthal, Jamie A.; Al‐Shaikhly, Taha

doi:10.1016/j.jaci.2020.12.128

Cited by 3 publications

(9 citation statements)

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“…The presence of allergic rhinitis does not alter the response to antihistamines. 12,13 Chang et al and Nebiolo et al in their studies found that hypertension is associated with an extended duration of disease and there is a higher risk of future hypertension in patients with chronic urticaria. 14,15 Not much research has been done in the past regarding this association.…”

Section: Discussionmentioning

confidence: 97%

Evaluation of D-dimer levels as a marker of chronic refractory urticaria and its correlation with disease severity

Kaur,

Margam,

Kaur

2024

IJCED

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: Chronic idiopathic urticaria (CIU) is very well managed by second-generation antihistamines in the majority of the cases but in a certain subset of patients symptoms persist despite their use. A deeper dig into disease pathogenesis will open new treatment options and better patient management. To evaluate D-Dimer as an anti-histaminic resistant chronic urticaria marker and its correlation with disease severity. Forty chronic urticaria patients attending skin OPD were enrolled and divided into 2 groups of 20 patients each according to response to antihistamines. D-dimer levels were done in each patient. Unpaired t-test was used for assessing two groups and Pearsons correlation coefficient was used to find correlation between D-Dimer levels and Urticaria activity score over 7 days (UAS-7).Result- D-dimer levels were significantly higher in group 1(chronic refractory urticaria) as compared to group 2(chronic urticaria) and there is a positive correlation between D-dimer levels and urticaria activity score (UAS7). Newer insights into alternative pathomechanism of chronic urticaria will open up new treatment options for treatment-resistant cases, this will lead to better patient management and improvement in quality of life.

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Section: Discussionmentioning

confidence: 97%

Evaluation of D-dimer levels as a marker of chronic refractory urticaria and its correlation with disease severity

Kaur,

Margam,

Kaur

2024

IJCED

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“…3; 95% CI, 24.2%-38.4%). 6,[11][12][13][14][16][17][18][19]22,23, The overall pooled prevalence of rhinitis in 7,055,142 reference individuals without urticaria was 19.8% (95% CI, 17.0%-22.6%; 9 studies). 14,16,17,23,42,45,50,56,61,66 Moreover, in patients with urticaria, the pooled prevalence of AR was 31.3% (95% CI 18.5%-44.1%; 31 studies) 6,[11][12][13][14][16][17][18][19]22,[40][41][42][43][44][46][47][48][49][50][51][52]54,56,58,59,61,62,…”

Section: Prevalence Of Rhinitis In Patients With Urticariamentioning

confidence: 99%

“…In total, 13 studies had a sample size of >1000 individuals, 14,17,[40][41][42]47,50,52,56,57,61,62,67 indicating a higher prevalence of rhinitis (32.5%; 95% CI, 20.8%-44.3%) than the 25 additional studies 6,[11][12][13]16,18,19,22,23,43,44,46,48,49,51,[53][54][55][58][59][60][63][64][65][66] with a sample size of <1000 individuals (28.9%; 95% CI, 23.9%-36.8%). A total of 11 studies 13,40,47,52,53,56,59,61,62,64,66 were cross-sectional, 10 were cohort studies, 6,…”

Section: Prevalence Of Rhinitis In Patients With Urticariamentioning

confidence: 99%

“…Only two studies 6,14 defined rhinitis and urticaria using a self-reported questionnaire completed by patients, and the pooled prevalence of rhinitis was 12.2% in patients with urticaria (95% CI, -2%-26.4%). The pooled prevalence was 27.4% (95% CI, 18.4%-36.3%) in 21 studies, [11][12][13]18,19,22,23,43,44,46,48,[51][52][53][54][55]57,59,60,65,67 in which rhinitis and/or urticaria were not specifically defined.…”

Section: Prevalence Of Rhinitis In Patients With Urticariamentioning

confidence: 99%

“…Most clinical re-searches have demonstrated that rhinitis was closely correlated with urticaria, [11][12][13][14][15][16][17][18][19][20] while others have reported otherwise. [21][22][23] Therefore, whether an atopic association between rhinitis and urticaria exists should be confirmed. Thus, this systematic review and meta-analysis aimed to quantify the prevalence and investigate the association between both aforementioned diseases.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and bidirectional association between rhinitis and urticaria: A systematic review and meta-analysis

Yongjun,

Xu,

et al. 2024

Preprint

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Background: Rhinitis, allergic rhinitis in particular, and urticaria are both common atopic problems globally. However, there is controversy regarding the correlation between rhinits and urticaria. Objectives: To examine the accurate association between rhinitis and urticaria. Methods: Three medical databases (PubMed, Embase, and Web of Science) were searched from database inception until January 11, 2022. The prevalence and association between rhinitis and urticaria were estimated by meta-analysis. The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed, and quality assessment was performed using the Newcastle–Ottawa Scale. Pooled odds ratios (OR) with 95% confidence intervals (95% CI) and pooled prevalence were calculated using random-effects models. Results: Urticaria prevalence in patients with rhinitis was 17.6% (95% CI, 13.2%–21.9%). The pooled prevalence of rhinitis was 31.3% (95% CI, 24.2%–38.4%) in patients with urticaria, and rhinitis prevalence in patients with acute urticaria and chronic urticaria was 31.6% (95% CI, 7.4%–55.8%) and 28.7% (95% CI, 20.4%–36.9%), respectively. Rhinitis occurence was significantly associated with urticaria (OR, 2.67; 95% CI, 2.625–2.715). Limitations: Urticaria and rhinitis were diagnosed based on different criteria possibly resulting in a potential misclassification of these two diseases. Conclusion: Rhinitis and urticaria were significantly correlated. Physicians should be cognizant regarding this relationship and address nasal or skin symptoms in patients.

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Prevalence and bidirectional association between rhinitis and urticaria: A systematic review and meta-analysis

Xu,

Lv,

Zeng

et al. 2023

allergy asthma proc

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Background: Rhinitis, allergic rhinitis in particular, and urticaria are both common diseases globally. However, there is controversy with regard to the correlation between rhinitis and urticaria. Objective: To examine the accurate association between rhinitis and urticaria. Methods: Three medical literature data bases were searched from data base inception until January 11, 2022. The prevalence and association between rhinitis and urticaria were estimated by meta-analysis. Quality assessment was performed by using the Newcastle‐Ottawa Scale. Pooled odds ratios (OR) with 95% confidence intervals (CI) and pooled prevalence were calculated by using random-effects models. Results: Urticaria prevalence in patients with rhinitis was 17.6% (95% CI, 13.2%‐21.9%). The pooled prevalence of rhinitis was 31.3% (95% CI, 24.2%‐38.4%) in patients with urticaria, and rhinitis prevalence in patients with acute urticaria and chronic urticaria was 31.6% (95% CI, 7.4%‐55.8%) and 28.7% (95% CI, 20.4%‐36.9%), respectively. Rhinitis occurrence was significantly associated with urticaria (OR 2.67 [95% CI, 2.625‐2.715]). Urticaria and rhinitis were diagnosed based on different criteria, possibly resulting in a potential error of misclassification. Conclusion: Rhinitis and urticaria were significantly correlated. Physicians should be cognizant with regard to this relationship and address nasal or skin symptoms in patients.

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Allergic Rhinitis and Chronic Spontaneous Urticaria

Cited by 3 publications

References 0 publications

Evaluation of D-dimer levels as a marker of chronic refractory urticaria and its correlation with disease severity

Evaluation of D-dimer levels as a marker of chronic refractory urticaria and its correlation with disease severity

Prevalence and bidirectional association between rhinitis and urticaria: A systematic review and meta-analysis

Prevalence and bidirectional association between rhinitis and urticaria: A systematic review and meta-analysis

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